Flucytosine for treatment of Candida albicans in H1N1-positive patient

A 17-year-old H1N1-positive patient was successfully extubated after 25 days of ventilatory support for treatment of viral pneumonia which was complicated by empyema thoracis due to Candida albicans. Hematogenous spread was suspected as simultaneous culture of ascitic fluid identified Candida specie...

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Detalles Bibliográficos
Autores principales: Samra, Tanvir, Yadav, Amlendu, Banerjee, Neerja, Pawar, Mridula, Deepak, Desh
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959217/
https://www.ncbi.nlm.nih.gov/pubmed/21206626
http://dx.doi.org/10.4103/0253-7613.70398
Descripción
Sumario:A 17-year-old H1N1-positive patient was successfully extubated after 25 days of ventilatory support for treatment of viral pneumonia which was complicated by empyema thoracis due to Candida albicans. Hematogenous spread was suspected as simultaneous culture of ascitic fluid identified Candida species sensitive to flucytosine but resistant to amphotericin B and azole group of antifungals. Monotherapy with flucytosine led to clinical and radiological improvement.

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