Flucytosine for treatment of Candida albicans in H1N1-positive patient

A 17-year-old H1N1-positive patient was successfully extubated after 25 days of ventilatory support for treatment of viral pneumonia which was complicated by empyema thoracis due to Candida albicans. Hematogenous spread was suspected as simultaneous culture of ascitic fluid identified Candida specie...

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Autores principales: Samra, Tanvir, Yadav, Amlendu, Banerjee, Neerja, Pawar, Mridula, Deepak, Desh
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959217/
https://www.ncbi.nlm.nih.gov/pubmed/21206626
http://dx.doi.org/10.4103/0253-7613.70398
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author Samra, Tanvir
Yadav, Amlendu
Banerjee, Neerja
Pawar, Mridula
Deepak, Desh
author_facet Samra, Tanvir
Yadav, Amlendu
Banerjee, Neerja
Pawar, Mridula
Deepak, Desh
author_sort Samra, Tanvir
collection PubMed
description A 17-year-old H1N1-positive patient was successfully extubated after 25 days of ventilatory support for treatment of viral pneumonia which was complicated by empyema thoracis due to Candida albicans. Hematogenous spread was suspected as simultaneous culture of ascitic fluid identified Candida species sensitive to flucytosine but resistant to amphotericin B and azole group of antifungals. Monotherapy with flucytosine led to clinical and radiological improvement.
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spelling pubmed-29592172011-01-04 Flucytosine for treatment of Candida albicans in H1N1-positive patient Samra, Tanvir Yadav, Amlendu Banerjee, Neerja Pawar, Mridula Deepak, Desh Indian J Pharmacol Drug Watch A 17-year-old H1N1-positive patient was successfully extubated after 25 days of ventilatory support for treatment of viral pneumonia which was complicated by empyema thoracis due to Candida albicans. Hematogenous spread was suspected as simultaneous culture of ascitic fluid identified Candida species sensitive to flucytosine but resistant to amphotericin B and azole group of antifungals. Monotherapy with flucytosine led to clinical and radiological improvement. Medknow Publications 2010-10 /pmc/articles/PMC2959217/ /pubmed/21206626 http://dx.doi.org/10.4103/0253-7613.70398 Text en © Indian Journal of Pharmacology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Drug Watch
Samra, Tanvir
Yadav, Amlendu
Banerjee, Neerja
Pawar, Mridula
Deepak, Desh
Flucytosine for treatment of Candida albicans in H1N1-positive patient
title Flucytosine for treatment of Candida albicans in H1N1-positive patient
title_full Flucytosine for treatment of Candida albicans in H1N1-positive patient
title_fullStr Flucytosine for treatment of Candida albicans in H1N1-positive patient
title_full_unstemmed Flucytosine for treatment of Candida albicans in H1N1-positive patient
title_short Flucytosine for treatment of Candida albicans in H1N1-positive patient
title_sort flucytosine for treatment of candida albicans in h1n1-positive patient
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959217/
https://www.ncbi.nlm.nih.gov/pubmed/21206626
http://dx.doi.org/10.4103/0253-7613.70398
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