Ethyl 1-(4-chloro­phen­yl)-3-[1-(4-meth­oxy­phen­yl)-4-oxo-3-phenyl­azetidin-2-yl]-2-nitro-2,3,10,10a-tetra­hydro-1H,5H-pyr­rolo[1,2-b]isoquinoline-10a-carboxyl­ate

In the title compound, C(37)H(34)ClN(3)O(6), the pyrrolidine and piperidine rings adopt envelope and boat conformations, respectively. The β-lactam ring is planar and forms dihedral angles of 21.3 (2) and 73.9 (2)°, respectively, with the attached methoxy­phenyl and phenyl rings. Intra­molecular C—H...

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Detalles Bibliográficos
Autores principales: Sundaresan, S., Ramesh, P., Arumugam, N., Raghunathan, R., Ponnuswamy, M. N.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959299/
https://www.ncbi.nlm.nih.gov/pubmed/21201234
http://dx.doi.org/10.1107/S1600536808030961
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author Sundaresan, S.
Ramesh, P.
Arumugam, N.
Raghunathan, R.
Ponnuswamy, M. N.
author_facet Sundaresan, S.
Ramesh, P.
Arumugam, N.
Raghunathan, R.
Ponnuswamy, M. N.
author_sort Sundaresan, S.
collection PubMed
description In the title compound, C(37)H(34)ClN(3)O(6), the pyrrolidine and piperidine rings adopt envelope and boat conformations, respectively. The β-lactam ring is planar and forms dihedral angles of 21.3 (2) and 73.9 (2)°, respectively, with the attached methoxy­phenyl and phenyl rings. Intra­molecular C—H⋯O and C—H⋯N hydrogen bonds are observed. Centrosym­metrically related mol­ecules are linked together by weak C—H⋯O hydrogen bonds to form dimers.
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spelling pubmed-29592992010-12-30 Ethyl 1-(4-chloro­phen­yl)-3-[1-(4-meth­oxy­phen­yl)-4-oxo-3-phenyl­azetidin-2-yl]-2-nitro-2,3,10,10a-tetra­hydro-1H,5H-pyr­rolo[1,2-b]isoquinoline-10a-carboxyl­ate Sundaresan, S. Ramesh, P. Arumugam, N. Raghunathan, R. Ponnuswamy, M. N. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(37)H(34)ClN(3)O(6), the pyrrolidine and piperidine rings adopt envelope and boat conformations, respectively. The β-lactam ring is planar and forms dihedral angles of 21.3 (2) and 73.9 (2)°, respectively, with the attached methoxy­phenyl and phenyl rings. Intra­molecular C—H⋯O and C—H⋯N hydrogen bonds are observed. Centrosym­metrically related mol­ecules are linked together by weak C—H⋯O hydrogen bonds to form dimers. International Union of Crystallography 2008-09-30 /pmc/articles/PMC2959299/ /pubmed/21201234 http://dx.doi.org/10.1107/S1600536808030961 Text en © Sundaresan et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Sundaresan, S.
Ramesh, P.
Arumugam, N.
Raghunathan, R.
Ponnuswamy, M. N.
Ethyl 1-(4-chloro­phen­yl)-3-[1-(4-meth­oxy­phen­yl)-4-oxo-3-phenyl­azetidin-2-yl]-2-nitro-2,3,10,10a-tetra­hydro-1H,5H-pyr­rolo[1,2-b]isoquinoline-10a-carboxyl­ate
title Ethyl 1-(4-chloro­phen­yl)-3-[1-(4-meth­oxy­phen­yl)-4-oxo-3-phenyl­azetidin-2-yl]-2-nitro-2,3,10,10a-tetra­hydro-1H,5H-pyr­rolo[1,2-b]isoquinoline-10a-carboxyl­ate
title_full Ethyl 1-(4-chloro­phen­yl)-3-[1-(4-meth­oxy­phen­yl)-4-oxo-3-phenyl­azetidin-2-yl]-2-nitro-2,3,10,10a-tetra­hydro-1H,5H-pyr­rolo[1,2-b]isoquinoline-10a-carboxyl­ate
title_fullStr Ethyl 1-(4-chloro­phen­yl)-3-[1-(4-meth­oxy­phen­yl)-4-oxo-3-phenyl­azetidin-2-yl]-2-nitro-2,3,10,10a-tetra­hydro-1H,5H-pyr­rolo[1,2-b]isoquinoline-10a-carboxyl­ate
title_full_unstemmed Ethyl 1-(4-chloro­phen­yl)-3-[1-(4-meth­oxy­phen­yl)-4-oxo-3-phenyl­azetidin-2-yl]-2-nitro-2,3,10,10a-tetra­hydro-1H,5H-pyr­rolo[1,2-b]isoquinoline-10a-carboxyl­ate
title_short Ethyl 1-(4-chloro­phen­yl)-3-[1-(4-meth­oxy­phen­yl)-4-oxo-3-phenyl­azetidin-2-yl]-2-nitro-2,3,10,10a-tetra­hydro-1H,5H-pyr­rolo[1,2-b]isoquinoline-10a-carboxyl­ate
title_sort ethyl 1-(4-chloro­phen­yl)-3-[1-(4-meth­oxy­phen­yl)-4-oxo-3-phenyl­azetidin-2-yl]-2-nitro-2,3,10,10a-tetra­hydro-1h,5h-pyr­rolo[1,2-b]isoquinoline-10a-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959299/
https://www.ncbi.nlm.nih.gov/pubmed/21201234
http://dx.doi.org/10.1107/S1600536808030961
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