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N-(2,6-Dimethyl-3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-2-hydroxy-2,2-diphenylacetamide
In the title compound, C(24)H(28)N(2)O(3)S, the pendant methyl C atom bonded to the cyclohexane ring is disordered over two sites in a 0.580 (11):0.420 (11) ratio. The cyclohexane ring adopts a distorted chair conformation while the thiazolidine ring has an envelope conformation. The two phenyl r...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959300/ https://www.ncbi.nlm.nih.gov/pubmed/21201127 http://dx.doi.org/10.1107/S1600536808028651 |
Sumario: | In the title compound, C(24)H(28)N(2)O(3)S, the pendant methyl C atom bonded to the cyclohexane ring is disordered over two sites in a 0.580 (11):0.420 (11) ratio. The cyclohexane ring adopts a distorted chair conformation while the thiazolidine ring has an envelope conformation. The two phenyl rings make a dihedral angle of 71.8 (2)° with each other. The conformation is stabilized by an intramolecular N—H⋯O hydrogen bond. In the crystal structure, an intermolecular hydrogen bond O—H⋯O occurs. |
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