N-(2,6-Dimethyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-2-hydr­oxy-2,2-di­phenyl­acetamide

In the title compound, C(24)H(28)N(2)O(3)S, the pendant methyl C atom bonded to the cyclo­hexane ring is disordered over two sites in a 0.580 (11):0.420 (11) ratio. The cyclo­hexane ring adopts a distorted chair conformation while the thia­zolidine ring has an envelope conformation. The two phenyl r...

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Detalles Bibliográficos
Autores principales: Yalçın, Şerife Pınar, Akkurt, Mehmet, Şahin, Ertan, Güzel, Özlen, Salman, Aydın, İhan, Eser
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959300/
https://www.ncbi.nlm.nih.gov/pubmed/21201127
http://dx.doi.org/10.1107/S1600536808028651
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author Yalçın, Şerife Pınar
Akkurt, Mehmet
Şahin, Ertan
Güzel, Özlen
Salman, Aydın
İhan, Eser
author_facet Yalçın, Şerife Pınar
Akkurt, Mehmet
Şahin, Ertan
Güzel, Özlen
Salman, Aydın
İhan, Eser
author_sort Yalçın, Şerife Pınar
collection PubMed
description In the title compound, C(24)H(28)N(2)O(3)S, the pendant methyl C atom bonded to the cyclo­hexane ring is disordered over two sites in a 0.580 (11):0.420 (11) ratio. The cyclo­hexane ring adopts a distorted chair conformation while the thia­zolidine ring has an envelope conformation. The two phenyl rings make a dihedral angle of 71.8 (2)° with each other. The conformation is stabilized by an intra­molecular N—H⋯O hydrogen bond. In the crystal structure, an inter­molecular hydrogen bond O—H⋯O occurs.
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spelling pubmed-29593002010-12-30 N-(2,6-Dimethyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-2-hydr­oxy-2,2-di­phenyl­acetamide Yalçın, Şerife Pınar Akkurt, Mehmet Şahin, Ertan Güzel, Özlen Salman, Aydın İhan, Eser Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(24)H(28)N(2)O(3)S, the pendant methyl C atom bonded to the cyclo­hexane ring is disordered over two sites in a 0.580 (11):0.420 (11) ratio. The cyclo­hexane ring adopts a distorted chair conformation while the thia­zolidine ring has an envelope conformation. The two phenyl rings make a dihedral angle of 71.8 (2)° with each other. The conformation is stabilized by an intra­molecular N—H⋯O hydrogen bond. In the crystal structure, an inter­molecular hydrogen bond O—H⋯O occurs. International Union of Crystallography 2008-09-13 /pmc/articles/PMC2959300/ /pubmed/21201127 http://dx.doi.org/10.1107/S1600536808028651 Text en © Yalçın et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Yalçın, Şerife Pınar
Akkurt, Mehmet
Şahin, Ertan
Güzel, Özlen
Salman, Aydın
İhan, Eser
N-(2,6-Dimethyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-2-hydr­oxy-2,2-di­phenyl­acetamide
title N-(2,6-Dimethyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-2-hydr­oxy-2,2-di­phenyl­acetamide
title_full N-(2,6-Dimethyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-2-hydr­oxy-2,2-di­phenyl­acetamide
title_fullStr N-(2,6-Dimethyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-2-hydr­oxy-2,2-di­phenyl­acetamide
title_full_unstemmed N-(2,6-Dimethyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-2-hydr­oxy-2,2-di­phenyl­acetamide
title_short N-(2,6-Dimethyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-2-hydr­oxy-2,2-di­phenyl­acetamide
title_sort n-(2,6-dimethyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-2-hydr­oxy-2,2-di­phenyl­acetamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959300/
https://www.ncbi.nlm.nih.gov/pubmed/21201127
http://dx.doi.org/10.1107/S1600536808028651
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AT ihaneser n26dimethyl3oxo1thia4azaspiro45dec4yl2hydroxy22diphenylacetamide

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