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(±)-N-(3-Hydr­oxy-1,2-diphenyl­prop­yl)-4-methyl­benzene­sulfonamide

In the title compound, C(22)H(23)NO(3)S, the relative stereochemistry of the two stereogenic centres is anti with respect to the H atoms. The mol­ecular packing of the crystal shows a double-strand arrangement, consisting of one strand of (S*,S*) enanti­omers and one strand of (R*,R*) enanti­omers....

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Detalles Bibliográficos
Autores principales: Tong, Sok Teng, Barker, David, Choi, Ka Wai, Boyd, Peter D. W., Brimble, Margaret A.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959308/
https://www.ncbi.nlm.nih.gov/pubmed/21201189
http://dx.doi.org/10.1107/S1600536808028948
Descripción
Sumario:In the title compound, C(22)H(23)NO(3)S, the relative stereochemistry of the two stereogenic centres is anti with respect to the H atoms. The mol­ecular packing of the crystal shows a double-strand arrangement, consisting of one strand of (S*,S*) enanti­omers and one strand of (R*,R*) enanti­omers. Both strands lie parallel to each other along the a axis. Each strand is made up of dimers in which the mol­ecules are connected to each other via an inter­molecular O—H⋯O hydrogen bond between the hydroxyl groups and an O—H⋯π inter­action with the aromatic ring. These units are then connected to neighbouring dimers via N—H⋯O hydrogen bonds and C—H⋯O interactions. Intramolecular C—H⋯O interactions are also observed.