Cargando…
(±)-N-(3-Hydroxy-1,2-diphenylpropyl)-4-methylbenzenesulfonamide
In the title compound, C(22)H(23)NO(3)S, the relative stereochemistry of the two stereogenic centres is anti with respect to the H atoms. The molecular packing of the crystal shows a double-strand arrangement, consisting of one strand of (S*,S*) enantiomers and one strand of (R*,R*) enantiomers....
Autores principales: | , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959308/ https://www.ncbi.nlm.nih.gov/pubmed/21201189 http://dx.doi.org/10.1107/S1600536808028948 |
_version_ | 1782188468521140224 |
---|---|
author | Tong, Sok Teng Barker, David Choi, Ka Wai Boyd, Peter D. W. Brimble, Margaret A. |
author_facet | Tong, Sok Teng Barker, David Choi, Ka Wai Boyd, Peter D. W. Brimble, Margaret A. |
author_sort | Tong, Sok Teng |
collection | PubMed |
description | In the title compound, C(22)H(23)NO(3)S, the relative stereochemistry of the two stereogenic centres is anti with respect to the H atoms. The molecular packing of the crystal shows a double-strand arrangement, consisting of one strand of (S*,S*) enantiomers and one strand of (R*,R*) enantiomers. Both strands lie parallel to each other along the a axis. Each strand is made up of dimers in which the molecules are connected to each other via an intermolecular O—H⋯O hydrogen bond between the hydroxyl groups and an O—H⋯π interaction with the aromatic ring. These units are then connected to neighbouring dimers via N—H⋯O hydrogen bonds and C—H⋯O interactions. Intramolecular C—H⋯O interactions are also observed. |
format | Text |
id | pubmed-2959308 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29593082010-12-30 (±)-N-(3-Hydroxy-1,2-diphenylpropyl)-4-methylbenzenesulfonamide Tong, Sok Teng Barker, David Choi, Ka Wai Boyd, Peter D. W. Brimble, Margaret A. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(22)H(23)NO(3)S, the relative stereochemistry of the two stereogenic centres is anti with respect to the H atoms. The molecular packing of the crystal shows a double-strand arrangement, consisting of one strand of (S*,S*) enantiomers and one strand of (R*,R*) enantiomers. Both strands lie parallel to each other along the a axis. Each strand is made up of dimers in which the molecules are connected to each other via an intermolecular O—H⋯O hydrogen bond between the hydroxyl groups and an O—H⋯π interaction with the aromatic ring. These units are then connected to neighbouring dimers via N—H⋯O hydrogen bonds and C—H⋯O interactions. Intramolecular C—H⋯O interactions are also observed. International Union of Crystallography 2008-09-24 /pmc/articles/PMC2959308/ /pubmed/21201189 http://dx.doi.org/10.1107/S1600536808028948 Text en © Tong et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Tong, Sok Teng Barker, David Choi, Ka Wai Boyd, Peter D. W. Brimble, Margaret A. (±)-N-(3-Hydroxy-1,2-diphenylpropyl)-4-methylbenzenesulfonamide |
title | (±)-N-(3-Hydroxy-1,2-diphenylpropyl)-4-methylbenzenesulfonamide |
title_full | (±)-N-(3-Hydroxy-1,2-diphenylpropyl)-4-methylbenzenesulfonamide |
title_fullStr | (±)-N-(3-Hydroxy-1,2-diphenylpropyl)-4-methylbenzenesulfonamide |
title_full_unstemmed | (±)-N-(3-Hydroxy-1,2-diphenylpropyl)-4-methylbenzenesulfonamide |
title_short | (±)-N-(3-Hydroxy-1,2-diphenylpropyl)-4-methylbenzenesulfonamide |
title_sort | (±)-n-(3-hydroxy-1,2-diphenylpropyl)-4-methylbenzenesulfonamide |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959308/ https://www.ncbi.nlm.nih.gov/pubmed/21201189 http://dx.doi.org/10.1107/S1600536808028948 |
work_keys_str_mv | AT tongsokteng n3hydroxy12diphenylpropyl4methylbenzenesulfonamide AT barkerdavid n3hydroxy12diphenylpropyl4methylbenzenesulfonamide AT choikawai n3hydroxy12diphenylpropyl4methylbenzenesulfonamide AT boydpeterdw n3hydroxy12diphenylpropyl4methylbenzenesulfonamide AT brimblemargareta n3hydroxy12diphenylpropyl4methylbenzenesulfonamide |