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(±)-N-(3-Hydr­oxy-1,2-diphenyl­prop­yl)-4-methyl­benzene­sulfonamide

In the title compound, C(22)H(23)NO(3)S, the relative stereochemistry of the two stereogenic centres is anti with respect to the H atoms. The mol­ecular packing of the crystal shows a double-strand arrangement, consisting of one strand of (S*,S*) enanti­omers and one strand of (R*,R*) enanti­omers....

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Detalles Bibliográficos
Autores principales: Tong, Sok Teng, Barker, David, Choi, Ka Wai, Boyd, Peter D. W., Brimble, Margaret A.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959308/
https://www.ncbi.nlm.nih.gov/pubmed/21201189
http://dx.doi.org/10.1107/S1600536808028948
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author Tong, Sok Teng
Barker, David
Choi, Ka Wai
Boyd, Peter D. W.
Brimble, Margaret A.
author_facet Tong, Sok Teng
Barker, David
Choi, Ka Wai
Boyd, Peter D. W.
Brimble, Margaret A.
author_sort Tong, Sok Teng
collection PubMed
description In the title compound, C(22)H(23)NO(3)S, the relative stereochemistry of the two stereogenic centres is anti with respect to the H atoms. The mol­ecular packing of the crystal shows a double-strand arrangement, consisting of one strand of (S*,S*) enanti­omers and one strand of (R*,R*) enanti­omers. Both strands lie parallel to each other along the a axis. Each strand is made up of dimers in which the mol­ecules are connected to each other via an inter­molecular O—H⋯O hydrogen bond between the hydroxyl groups and an O—H⋯π inter­action with the aromatic ring. These units are then connected to neighbouring dimers via N—H⋯O hydrogen bonds and C—H⋯O interactions. Intramolecular C—H⋯O interactions are also observed.
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spelling pubmed-29593082010-12-30 (±)-N-(3-Hydr­oxy-1,2-diphenyl­prop­yl)-4-methyl­benzene­sulfonamide Tong, Sok Teng Barker, David Choi, Ka Wai Boyd, Peter D. W. Brimble, Margaret A. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(22)H(23)NO(3)S, the relative stereochemistry of the two stereogenic centres is anti with respect to the H atoms. The mol­ecular packing of the crystal shows a double-strand arrangement, consisting of one strand of (S*,S*) enanti­omers and one strand of (R*,R*) enanti­omers. Both strands lie parallel to each other along the a axis. Each strand is made up of dimers in which the mol­ecules are connected to each other via an inter­molecular O—H⋯O hydrogen bond between the hydroxyl groups and an O—H⋯π inter­action with the aromatic ring. These units are then connected to neighbouring dimers via N—H⋯O hydrogen bonds and C—H⋯O interactions. Intramolecular C—H⋯O interactions are also observed. International Union of Crystallography 2008-09-24 /pmc/articles/PMC2959308/ /pubmed/21201189 http://dx.doi.org/10.1107/S1600536808028948 Text en © Tong et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Tong, Sok Teng
Barker, David
Choi, Ka Wai
Boyd, Peter D. W.
Brimble, Margaret A.
(±)-N-(3-Hydr­oxy-1,2-diphenyl­prop­yl)-4-methyl­benzene­sulfonamide
title (±)-N-(3-Hydr­oxy-1,2-diphenyl­prop­yl)-4-methyl­benzene­sulfonamide
title_full (±)-N-(3-Hydr­oxy-1,2-diphenyl­prop­yl)-4-methyl­benzene­sulfonamide
title_fullStr (±)-N-(3-Hydr­oxy-1,2-diphenyl­prop­yl)-4-methyl­benzene­sulfonamide
title_full_unstemmed (±)-N-(3-Hydr­oxy-1,2-diphenyl­prop­yl)-4-methyl­benzene­sulfonamide
title_short (±)-N-(3-Hydr­oxy-1,2-diphenyl­prop­yl)-4-methyl­benzene­sulfonamide
title_sort (±)-n-(3-hydr­oxy-1,2-diphenyl­prop­yl)-4-methyl­benzene­sulfonamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959308/
https://www.ncbi.nlm.nih.gov/pubmed/21201189
http://dx.doi.org/10.1107/S1600536808028948
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