Methyl trans-rac-2-hexyl-1-oxo-3-(2-pyrid­yl)-1,2,3,4-tetra­hydroisoquinoline-4-carboxyl­ate

The title compound, C(22)H(26)N(2)O(3), was synthesized by esterification of trans-rac-2-hexyl-1-oxo-3-(2-pyrid­yl)-1,2,3,4-tetra­hydro­isoquinoline-4-carboxylic acid in the presence of H(2)SO(4) in methanol. The dihedral angle between the benzene and pyridine rings is 84.46 (17)°. The piperidine ri...

Descripción completa

Detalles Bibliográficos
Autores principales: Yıldırım, Sema Öztürk, Akkurt, Mehmet, Kandinska, Meglena I., Bogdanov, Milen G., Büyükgüngör, Orhan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959350/
https://www.ncbi.nlm.nih.gov/pubmed/21201140
http://dx.doi.org/10.1107/S1600536808029048
_version_ 1782188478453252096
author Yıldırım, Sema Öztürk
Akkurt, Mehmet
Kandinska, Meglena I.
Bogdanov, Milen G.
Büyükgüngör, Orhan
author_facet Yıldırım, Sema Öztürk
Akkurt, Mehmet
Kandinska, Meglena I.
Bogdanov, Milen G.
Büyükgüngör, Orhan
author_sort Yıldırım, Sema Öztürk
collection PubMed
description The title compound, C(22)H(26)N(2)O(3), was synthesized by esterification of trans-rac-2-hexyl-1-oxo-3-(2-pyrid­yl)-1,2,3,4-tetra­hydro­isoquinoline-4-carboxylic acid in the presence of H(2)SO(4) in methanol. The dihedral angle between the benzene and pyridine rings is 84.46 (17)°. The piperidine ring adopts a screw-boat conformation. In the crystal, inversion dimers linked by two C—H⋯O bonds occur.
format Text
id pubmed-2959350
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29593502010-12-30 Methyl trans-rac-2-hexyl-1-oxo-3-(2-pyrid­yl)-1,2,3,4-tetra­hydroisoquinoline-4-carboxyl­ate Yıldırım, Sema Öztürk Akkurt, Mehmet Kandinska, Meglena I. Bogdanov, Milen G. Büyükgüngör, Orhan Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(22)H(26)N(2)O(3), was synthesized by esterification of trans-rac-2-hexyl-1-oxo-3-(2-pyrid­yl)-1,2,3,4-tetra­hydro­isoquinoline-4-carboxylic acid in the presence of H(2)SO(4) in methanol. The dihedral angle between the benzene and pyridine rings is 84.46 (17)°. The piperidine ring adopts a screw-boat conformation. In the crystal, inversion dimers linked by two C—H⋯O bonds occur. International Union of Crystallography 2008-09-13 /pmc/articles/PMC2959350/ /pubmed/21201140 http://dx.doi.org/10.1107/S1600536808029048 Text en © Yıldırım et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Yıldırım, Sema Öztürk
Akkurt, Mehmet
Kandinska, Meglena I.
Bogdanov, Milen G.
Büyükgüngör, Orhan
Methyl trans-rac-2-hexyl-1-oxo-3-(2-pyrid­yl)-1,2,3,4-tetra­hydroisoquinoline-4-carboxyl­ate
title Methyl trans-rac-2-hexyl-1-oxo-3-(2-pyrid­yl)-1,2,3,4-tetra­hydroisoquinoline-4-carboxyl­ate
title_full Methyl trans-rac-2-hexyl-1-oxo-3-(2-pyrid­yl)-1,2,3,4-tetra­hydroisoquinoline-4-carboxyl­ate
title_fullStr Methyl trans-rac-2-hexyl-1-oxo-3-(2-pyrid­yl)-1,2,3,4-tetra­hydroisoquinoline-4-carboxyl­ate
title_full_unstemmed Methyl trans-rac-2-hexyl-1-oxo-3-(2-pyrid­yl)-1,2,3,4-tetra­hydroisoquinoline-4-carboxyl­ate
title_short Methyl trans-rac-2-hexyl-1-oxo-3-(2-pyrid­yl)-1,2,3,4-tetra­hydroisoquinoline-4-carboxyl­ate
title_sort methyl trans-rac-2-hexyl-1-oxo-3-(2-pyrid­yl)-1,2,3,4-tetra­hydroisoquinoline-4-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959350/
https://www.ncbi.nlm.nih.gov/pubmed/21201140
http://dx.doi.org/10.1107/S1600536808029048
work_keys_str_mv AT yıldırımsemaozturk methyltransrac2hexyl1oxo32pyridyl1234tetrahydroisoquinoline4carboxylate
AT akkurtmehmet methyltransrac2hexyl1oxo32pyridyl1234tetrahydroisoquinoline4carboxylate
AT kandinskameglenai methyltransrac2hexyl1oxo32pyridyl1234tetrahydroisoquinoline4carboxylate
AT bogdanovmileng methyltransrac2hexyl1oxo32pyridyl1234tetrahydroisoquinoline4carboxylate
AT buyukgungororhan methyltransrac2hexyl1oxo32pyridyl1234tetrahydroisoquinoline4carboxylate

Ejemplares similares