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trans-rac-[1-Oxo-2-phenethyl-3-(2-thien­yl)-1,2,3,4-tetra­hydro­isoquinolin-4-yl]methyl 4-methyl­benzene­sulfonate

The title compound, C(29)H(27)NO(4)S(2), was synthesized by reaction of trans-rac-4-(hydroxy­meth­yl)-2-phenethyl-3-(thio­phen-2-yl)-3,4-dihydro­isoquinolin-1(2H)-one and 4-methyl­benzene-1-sulfonyl chloride in the presence of Et(3)N in CH(2)Cl(2). The relative orientations of the benzene ring (A) o...

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Detalles Bibliográficos
Autores principales: Akkurt, Mehmet, Öztürk Yıldırım, Sema, Bogdanov, Milen G., Kandinska, Meglena I., Büyükgüngör, Orhan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959401/
https://www.ncbi.nlm.nih.gov/pubmed/21201159
http://dx.doi.org/10.1107/S1600536808029309
Descripción
Sumario:The title compound, C(29)H(27)NO(4)S(2), was synthesized by reaction of trans-rac-4-(hydroxy­meth­yl)-2-phenethyl-3-(thio­phen-2-yl)-3,4-dihydro­isoquinolin-1(2H)-one and 4-methyl­benzene-1-sulfonyl chloride in the presence of Et(3)N in CH(2)Cl(2). The relative orientations of the benzene ring (A) of the 3,4-dihydro­isoquinolinone ring system, the thio­phene ring (B), the benzene ring (C) of the methyl­benzene group and the phenyl ring (D) result in the following dihedral angles: A/B = 80.91 (16), A/C = 22.79 (18), A/D = 9.9 (2), B/C = 80.73 (19), B/D = 88.9 (2) and C/D = 29.9 (2)°. The crystal structure is stabilized by weak inter­molecular C—H⋯O hydrogen bonds and C—H⋯π inter­actions.