(Z)-4-[3-(3-Oxoquinuclidin-2-ylidene­meth­yl)-1H-indol-1-ylmeth­yl]benzo­nitrile

The title compound, C(24)H(21)N(3)O, was prepared by the reaction of (Z)-2-(1H-indol-3-ylmethyl­ene)-1-aza­bicyclo­[2.2.2]octan-3-one with α-bromo-p-toluonitrile, under phase-transfer catalytic (PTC) conditions using triethyl­benzyl­ammonium chloride and 50% w/v aqueous NaOH solution in dichloro­met...

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Detalles Bibliográficos
Autores principales: Reddy, Thirupathi Reddy Yerram, Penthala, Narsimha Reddy, Parkin, Sean, Crooks, Peter A.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959535/
https://www.ncbi.nlm.nih.gov/pubmed/21580917
http://dx.doi.org/10.1107/S1600536808030006
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author Reddy, Thirupathi Reddy Yerram
Penthala, Narsimha Reddy
Parkin, Sean
Crooks, Peter A.
author_facet Reddy, Thirupathi Reddy Yerram
Penthala, Narsimha Reddy
Parkin, Sean
Crooks, Peter A.
author_sort Reddy, Thirupathi Reddy Yerram
collection PubMed
description The title compound, C(24)H(21)N(3)O, was prepared by the reaction of (Z)-2-(1H-indol-3-ylmethyl­ene)-1-aza­bicyclo­[2.2.2]octan-3-one with α-bromo-p-toluonitrile, under phase-transfer catalytic (PTC) conditions using triethyl­benzyl­ammonium chloride and 50% w/v aqueous NaOH solution in dichloro­methane. The crystal structure indicates the presence of a double bond with Z geometry connecting the aza­bicyclic and indole groups.
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spelling pubmed-29595352010-12-30 (Z)-4-[3-(3-Oxoquinuclidin-2-ylidene­meth­yl)-1H-indol-1-ylmeth­yl]benzo­nitrile Reddy, Thirupathi Reddy Yerram Penthala, Narsimha Reddy Parkin, Sean Crooks, Peter A. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(24)H(21)N(3)O, was prepared by the reaction of (Z)-2-(1H-indol-3-ylmethyl­ene)-1-aza­bicyclo­[2.2.2]octan-3-one with α-bromo-p-toluonitrile, under phase-transfer catalytic (PTC) conditions using triethyl­benzyl­ammonium chloride and 50% w/v aqueous NaOH solution in dichloro­methane. The crystal structure indicates the presence of a double bond with Z geometry connecting the aza­bicyclic and indole groups. International Union of Crystallography 2008-10-04 /pmc/articles/PMC2959535/ /pubmed/21580917 http://dx.doi.org/10.1107/S1600536808030006 Text en © Reddy et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Reddy, Thirupathi Reddy Yerram
Penthala, Narsimha Reddy
Parkin, Sean
Crooks, Peter A.
(Z)-4-[3-(3-Oxoquinuclidin-2-ylidene­meth­yl)-1H-indol-1-ylmeth­yl]benzo­nitrile
title (Z)-4-[3-(3-Oxoquinuclidin-2-ylidene­meth­yl)-1H-indol-1-ylmeth­yl]benzo­nitrile
title_full (Z)-4-[3-(3-Oxoquinuclidin-2-ylidene­meth­yl)-1H-indol-1-ylmeth­yl]benzo­nitrile
title_fullStr (Z)-4-[3-(3-Oxoquinuclidin-2-ylidene­meth­yl)-1H-indol-1-ylmeth­yl]benzo­nitrile
title_full_unstemmed (Z)-4-[3-(3-Oxoquinuclidin-2-ylidene­meth­yl)-1H-indol-1-ylmeth­yl]benzo­nitrile
title_short (Z)-4-[3-(3-Oxoquinuclidin-2-ylidene­meth­yl)-1H-indol-1-ylmeth­yl]benzo­nitrile
title_sort (z)-4-[3-(3-oxoquinuclidin-2-ylidene­meth­yl)-1h-indol-1-ylmeth­yl]benzo­nitrile
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959535/
https://www.ncbi.nlm.nih.gov/pubmed/21580917
http://dx.doi.org/10.1107/S1600536808030006
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AT penthalanarsimhareddy z433oxoquinuclidin2ylidenemethyl1hindol1ylmethylbenzonitrile
AT parkinsean z433oxoquinuclidin2ylidenemethyl1hindol1ylmethylbenzonitrile
AT crookspetera z433oxoquinuclidin2ylidenemethyl1hindol1ylmethylbenzonitrile

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