Cargando…

4-Chloro-2-((1R)-1-{[(R)-(2-chloro­phen­yl)(cyclo­pent­yl)meth­yl]amino}eth­yl)phenol

The title compound, C(20)H(23)Cl(2)NO, was prepared by condensation of (R)-1-(2-chloro­phen­yl)-1-cyclo­pentyl­methanamine with 1-(5-chloro-2-hydroxy­phen­yl)ethanone, resulting in the formation of a new chiral center. The structural analysis confirms the absolute configuration of the title compound...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Guang-You, Yang, Ting, Xu, Bao-Wang, Chen, Di-Juan, Wang, Wan-Hui
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959664/
https://www.ncbi.nlm.nih.gov/pubmed/21581069
http://dx.doi.org/10.1107/S1600536808034624
Descripción
Sumario:The title compound, C(20)H(23)Cl(2)NO, was prepared by condensation of (R)-1-(2-chloro­phen­yl)-1-cyclo­pentyl­methanamine with 1-(5-chloro-2-hydroxy­phen­yl)ethanone, resulting in the formation of a new chiral center. The structural analysis confirms the absolute configuration of the title compound and the formation of the (R,R) diastereoisomer. There is an intra­molecular O—H⋯N hydrogen bond which stabilizes the conformation of the mol­ecule. The mol­ecules are linked to each other through weak C—H⋯π inter­actions.