Cargando…
4-Chloro-2-((1R)-1-{[(R)-(2-chlorophenyl)(cyclopentyl)methyl]amino}ethyl)phenol
The title compound, C(20)H(23)Cl(2)NO, was prepared by condensation of (R)-1-(2-chlorophenyl)-1-cyclopentylmethanamine with 1-(5-chloro-2-hydroxyphenyl)ethanone, resulting in the formation of a new chiral center. The structural analysis confirms the absolute configuration of the title compound...
Autores principales: | , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959664/ https://www.ncbi.nlm.nih.gov/pubmed/21581069 http://dx.doi.org/10.1107/S1600536808034624 |
Sumario: | The title compound, C(20)H(23)Cl(2)NO, was prepared by condensation of (R)-1-(2-chlorophenyl)-1-cyclopentylmethanamine with 1-(5-chloro-2-hydroxyphenyl)ethanone, resulting in the formation of a new chiral center. The structural analysis confirms the absolute configuration of the title compound and the formation of the (R,R) diastereoisomer. There is an intramolecular O—H⋯N hydrogen bond which stabilizes the conformation of the molecule. The molecules are linked to each other through weak C—H⋯π interactions. |
---|