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N-{N-[N-(1,1-Dimethylethoxycarbonyl)-l-leucyl]-N-methyl-l-leucyl}-N-methyl-l-leucine benzyl ester
The tripeptide title compound, C(32)H(53)N(3)O(6), synthesized in 80% yield by coupling of N-methyl-l-leucine benzyl ester with tert-butoxycarbonyl-l-leucyl-N-methyl-l-leucine at 273 K, conjugates through two amide linkages and includes two protecting groups: a tert-butyloxycarbonyl group at the C...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959758/ https://www.ncbi.nlm.nih.gov/pubmed/21581037 http://dx.doi.org/10.1107/S1600536808034247 |
Sumario: | The tripeptide title compound, C(32)H(53)N(3)O(6), synthesized in 80% yield by coupling of N-methyl-l-leucine benzyl ester with tert-butoxycarbonyl-l-leucyl-N-methyl-l-leucine at 273 K, conjugates through two amide linkages and includes two protecting groups: a tert-butyloxycarbonyl group at the C-tip and a benzyl group at the N-tip. A classical intermolecular N—H⋯O hydrogen bond and a weak non-conventional intermolecular C—H⋯O contact connect the molecules, forming layers parallel to (001). |
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