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tert-Butyl 2-(3-acetyl­amino-2-oxo-1,2-dihydro-1-pyrid­yl)acetate

The title compound, C(13)H(18)N(2)O(4), crystallizes as discrete mol­ecules associated as N—H⋯O hydrogen-bonded dimers disposed about a crystallographic inversion centre. The structure is the first solid-state structure for a 3-acetyl­pyridone without C-4 to C-6 substituents. The amide subsituent at...

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Detalles Bibliográficos
Autores principales: Karis, N. David, Loughlin, Wendy A., Jenkins, Ian D., Healy, Peter C.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959903/
https://www.ncbi.nlm.nih.gov/pubmed/21581454
http://dx.doi.org/10.1107/S1600536808039810
Descripción
Sumario:The title compound, C(13)H(18)N(2)O(4), crystallizes as discrete mol­ecules associated as N—H⋯O hydrogen-bonded dimers disposed about a crystallographic inversion centre. The structure is the first solid-state structure for a 3-acetyl­pyridone without C-4 to C-6 substituents. The amide subsituent at C-3 is coplanar with the pyridone ring, while the tert-butyl ester group is orthogonal to the pyridine ring. The amide and ester carbonyl O atoms are not involved in strong hydrogen bonding with only a number of intramolecular and intermolecular C—H⋯O inter­actions apparent in the structure.