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{5-Methyl-1-[8-(trifluoro­meth­yl)quinolin-4-yl]-1H-1,2,3-triazol-4-yl}(morpholino)methanone

In the title mol­ecule, C(18)H(16)F(3)N(5)O(2), the dihedral angle between the pyridine ring and the fused benzene ring is 4.50 (10)°. The triazole ring makes dihedral angles of 54.48 (12) and 57.91 (11)° with the pyridine and benzene rings, respectively. The morpholine ring atoms are disordered ove...

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Detalles Bibliográficos
Autores principales: Anuradha, N., Thiruvalluvar, A., Mahalinga, M., Butcher, R. J.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959961/
https://www.ncbi.nlm.nih.gov/pubmed/21581347
http://dx.doi.org/10.1107/S1600536808037562
Descripción
Sumario:In the title mol­ecule, C(18)H(16)F(3)N(5)O(2), the dihedral angle between the pyridine ring and the fused benzene ring is 4.50 (10)°. The triazole ring makes dihedral angles of 54.48 (12) and 57.91 (11)° with the pyridine and benzene rings, respectively. The morpholine ring atoms are disordered over two positions; the site-occupancy factors are ca 0.53 and 0.47. Inter­molecular C—H⋯F hydrogen bonding is found in the crystal structure. Furthermore, C—H⋯O and C—H⋯N intra­molecular contacts are also present.