{5-Methyl-1-[8-(trifluoro­meth­yl)quinolin-4-yl]-1H-1,2,3-triazol-4-yl}(morpholino)methanone

In the title mol­ecule, C(18)H(16)F(3)N(5)O(2), the dihedral angle between the pyridine ring and the fused benzene ring is 4.50 (10)°. The triazole ring makes dihedral angles of 54.48 (12) and 57.91 (11)° with the pyridine and benzene rings, respectively. The morpholine ring atoms are disordered ove...

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Detalles Bibliográficos
Autores principales: Anuradha, N., Thiruvalluvar, A., Mahalinga, M., Butcher, R. J.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959961/
https://www.ncbi.nlm.nih.gov/pubmed/21581347
http://dx.doi.org/10.1107/S1600536808037562
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author Anuradha, N.
Thiruvalluvar, A.
Mahalinga, M.
Butcher, R. J.
author_facet Anuradha, N.
Thiruvalluvar, A.
Mahalinga, M.
Butcher, R. J.
author_sort Anuradha, N.
collection PubMed
description In the title mol­ecule, C(18)H(16)F(3)N(5)O(2), the dihedral angle between the pyridine ring and the fused benzene ring is 4.50 (10)°. The triazole ring makes dihedral angles of 54.48 (12) and 57.91 (11)° with the pyridine and benzene rings, respectively. The morpholine ring atoms are disordered over two positions; the site-occupancy factors are ca 0.53 and 0.47. Inter­molecular C—H⋯F hydrogen bonding is found in the crystal structure. Furthermore, C—H⋯O and C—H⋯N intra­molecular contacts are also present.
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spelling pubmed-29599612010-12-30 {5-Methyl-1-[8-(trifluoro­meth­yl)quinolin-4-yl]-1H-1,2,3-triazol-4-yl}(morpholino)methanone Anuradha, N. Thiruvalluvar, A. Mahalinga, M. Butcher, R. J. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title mol­ecule, C(18)H(16)F(3)N(5)O(2), the dihedral angle between the pyridine ring and the fused benzene ring is 4.50 (10)°. The triazole ring makes dihedral angles of 54.48 (12) and 57.91 (11)° with the pyridine and benzene rings, respectively. The morpholine ring atoms are disordered over two positions; the site-occupancy factors are ca 0.53 and 0.47. Inter­molecular C—H⋯F hydrogen bonding is found in the crystal structure. Furthermore, C—H⋯O and C—H⋯N intra­molecular contacts are also present. International Union of Crystallography 2008-11-20 /pmc/articles/PMC2959961/ /pubmed/21581347 http://dx.doi.org/10.1107/S1600536808037562 Text en © Anuradha et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Anuradha, N.
Thiruvalluvar, A.
Mahalinga, M.
Butcher, R. J.
{5-Methyl-1-[8-(trifluoro­meth­yl)quinolin-4-yl]-1H-1,2,3-triazol-4-yl}(morpholino)methanone
title {5-Methyl-1-[8-(trifluoro­meth­yl)quinolin-4-yl]-1H-1,2,3-triazol-4-yl}(morpholino)methanone
title_full {5-Methyl-1-[8-(trifluoro­meth­yl)quinolin-4-yl]-1H-1,2,3-triazol-4-yl}(morpholino)methanone
title_fullStr {5-Methyl-1-[8-(trifluoro­meth­yl)quinolin-4-yl]-1H-1,2,3-triazol-4-yl}(morpholino)methanone
title_full_unstemmed {5-Methyl-1-[8-(trifluoro­meth­yl)quinolin-4-yl]-1H-1,2,3-triazol-4-yl}(morpholino)methanone
title_short {5-Methyl-1-[8-(trifluoro­meth­yl)quinolin-4-yl]-1H-1,2,3-triazol-4-yl}(morpholino)methanone
title_sort {5-methyl-1-[8-(trifluoro­meth­yl)quinolin-4-yl]-1h-1,2,3-triazol-4-yl}(morpholino)methanone
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959961/
https://www.ncbi.nlm.nih.gov/pubmed/21581347
http://dx.doi.org/10.1107/S1600536808037562
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AT mahalingam 5methyl18trifluoromethylquinolin4yl1h123triazol4ylmorpholinomethanone
AT butcherrj 5methyl18trifluoromethylquinolin4yl1h123triazol4ylmorpholinomethanone

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