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(S)-2-[(2R,3S)-2-Ammonio-3-hydroxy-3-(4-nitrophenyl)propanamido]-4-methylpentanoate monohydrate
The structure of the title compound, C(15)H(21)N(3)O(6)·H(2)O, is of interest with respect to assumed anticancer activity. The title molecules are linked through intermolecular O—H⋯O hydrogen-bonded chains along the a axis. These chains are connected by intermolecular N—H⋯O hydrogen bonds throu...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960037/ https://www.ncbi.nlm.nih.gov/pubmed/21581415 http://dx.doi.org/10.1107/S1600536808039056 |
Sumario: | The structure of the title compound, C(15)H(21)N(3)O(6)·H(2)O, is of interest with respect to assumed anticancer activity. The title molecules are linked through intermolecular O—H⋯O hydrogen-bonded chains along the a axis. These chains are connected by intermolecular N—H⋯O hydrogen bonds through the crystallographic screw axis along [010], forming layers, which are stabilized by other N—H⋯O bonds with water O atoms as acceptors and O—H⋯O bonds with water H atoms as donors. The H atoms of the protonated amino cation are also involved in intermolecular N—H⋯O bonding interactions. |
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