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(S)-2-[(2R,3S)-2-Ammonio-3-hydroxy-3-(4-nitrophenyl)propanamido]-4-methylpentanoate monohydrate
The structure of the title compound, C(15)H(21)N(3)O(6)·H(2)O, is of interest with respect to assumed anticancer activity. The title molecules are linked through intermolecular O—H⋯O hydrogen-bonded chains along the a axis. These chains are connected by intermolecular N—H⋯O hydrogen bonds throu...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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International Union of Crystallography
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960037/ https://www.ncbi.nlm.nih.gov/pubmed/21581415 http://dx.doi.org/10.1107/S1600536808039056 |
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author | Yang, Kang-Hui Li, Xun Gong, Jian-Zhi Fang, Hao Xu, Wen-Fang |
author_facet | Yang, Kang-Hui Li, Xun Gong, Jian-Zhi Fang, Hao Xu, Wen-Fang |
author_sort | Yang, Kang-Hui |
collection | PubMed |
description | The structure of the title compound, C(15)H(21)N(3)O(6)·H(2)O, is of interest with respect to assumed anticancer activity. The title molecules are linked through intermolecular O—H⋯O hydrogen-bonded chains along the a axis. These chains are connected by intermolecular N—H⋯O hydrogen bonds through the crystallographic screw axis along [010], forming layers, which are stabilized by other N—H⋯O bonds with water O atoms as acceptors and O—H⋯O bonds with water H atoms as donors. The H atoms of the protonated amino cation are also involved in intermolecular N—H⋯O bonding interactions. |
format | Text |
id | pubmed-2960037 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29600372010-12-30 (S)-2-[(2R,3S)-2-Ammonio-3-hydroxy-3-(4-nitrophenyl)propanamido]-4-methylpentanoate monohydrate Yang, Kang-Hui Li, Xun Gong, Jian-Zhi Fang, Hao Xu, Wen-Fang Acta Crystallogr Sect E Struct Rep Online Organic Papers The structure of the title compound, C(15)H(21)N(3)O(6)·H(2)O, is of interest with respect to assumed anticancer activity. The title molecules are linked through intermolecular O—H⋯O hydrogen-bonded chains along the a axis. These chains are connected by intermolecular N—H⋯O hydrogen bonds through the crystallographic screw axis along [010], forming layers, which are stabilized by other N—H⋯O bonds with water O atoms as acceptors and O—H⋯O bonds with water H atoms as donors. The H atoms of the protonated amino cation are also involved in intermolecular N—H⋯O bonding interactions. International Union of Crystallography 2008-11-26 /pmc/articles/PMC2960037/ /pubmed/21581415 http://dx.doi.org/10.1107/S1600536808039056 Text en © Yang et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Yang, Kang-Hui Li, Xun Gong, Jian-Zhi Fang, Hao Xu, Wen-Fang (S)-2-[(2R,3S)-2-Ammonio-3-hydroxy-3-(4-nitrophenyl)propanamido]-4-methylpentanoate monohydrate |
title | (S)-2-[(2R,3S)-2-Ammonio-3-hydroxy-3-(4-nitrophenyl)propanamido]-4-methylpentanoate monohydrate |
title_full | (S)-2-[(2R,3S)-2-Ammonio-3-hydroxy-3-(4-nitrophenyl)propanamido]-4-methylpentanoate monohydrate |
title_fullStr | (S)-2-[(2R,3S)-2-Ammonio-3-hydroxy-3-(4-nitrophenyl)propanamido]-4-methylpentanoate monohydrate |
title_full_unstemmed | (S)-2-[(2R,3S)-2-Ammonio-3-hydroxy-3-(4-nitrophenyl)propanamido]-4-methylpentanoate monohydrate |
title_short | (S)-2-[(2R,3S)-2-Ammonio-3-hydroxy-3-(4-nitrophenyl)propanamido]-4-methylpentanoate monohydrate |
title_sort | (s)-2-[(2r,3s)-2-ammonio-3-hydroxy-3-(4-nitrophenyl)propanamido]-4-methylpentanoate monohydrate |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960037/ https://www.ncbi.nlm.nih.gov/pubmed/21581415 http://dx.doi.org/10.1107/S1600536808039056 |
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