tert-Butyl 4-carbamoyl-3-methoxy­imino-4-methyl­piperidine-1-carboxyl­ate

The title compound, C(13)H(23)N(3)O(4), was prepared starting from ethyl N-benzyl-3-oxopiperidine-4-carboxyl­ate through a nine-step reaction, including hydrogenation, Boc (tert-butoxy­carbon­yl) protection, methyl­ation, oximation, hydrolysis, esterification and ammonolysis. In the crystal structur...

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Detalles Bibliográficos
Autores principales: Wang, Juxian, Liu, Mingliang, Cao, Jue, Wang, Yucheng
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960090/
https://www.ncbi.nlm.nih.gov/pubmed/21581272
http://dx.doi.org/10.1107/S1600536808036106
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author Wang, Juxian
Liu, Mingliang
Cao, Jue
Wang, Yucheng
author_facet Wang, Juxian
Liu, Mingliang
Cao, Jue
Wang, Yucheng
author_sort Wang, Juxian
collection PubMed
description The title compound, C(13)H(23)N(3)O(4), was prepared starting from ethyl N-benzyl-3-oxopiperidine-4-carboxyl­ate through a nine-step reaction, including hydrogenation, Boc (tert-butoxy­carbon­yl) protection, methyl­ation, oximation, hydrolysis, esterification and ammonolysis. In the crystal structure, mol­ecules are linked by inter­molecular N—H⋯O hydrogen bonds to form a porous three-dimensional network with solvent-free hydro­phobic channels extending along the c axis.
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spelling pubmed-29600902010-12-30 tert-Butyl 4-carbamoyl-3-methoxy­imino-4-methyl­piperidine-1-carboxyl­ate Wang, Juxian Liu, Mingliang Cao, Jue Wang, Yucheng Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(13)H(23)N(3)O(4), was prepared starting from ethyl N-benzyl-3-oxopiperidine-4-carboxyl­ate through a nine-step reaction, including hydrogenation, Boc (tert-butoxy­carbon­yl) protection, methyl­ation, oximation, hydrolysis, esterification and ammonolysis. In the crystal structure, mol­ecules are linked by inter­molecular N—H⋯O hydrogen bonds to form a porous three-dimensional network with solvent-free hydro­phobic channels extending along the c axis. International Union of Crystallography 2008-11-08 /pmc/articles/PMC2960090/ /pubmed/21581272 http://dx.doi.org/10.1107/S1600536808036106 Text en © Wang et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wang, Juxian
Liu, Mingliang
Cao, Jue
Wang, Yucheng
tert-Butyl 4-carbamoyl-3-methoxy­imino-4-methyl­piperidine-1-carboxyl­ate
title tert-Butyl 4-carbamoyl-3-methoxy­imino-4-methyl­piperidine-1-carboxyl­ate
title_full tert-Butyl 4-carbamoyl-3-methoxy­imino-4-methyl­piperidine-1-carboxyl­ate
title_fullStr tert-Butyl 4-carbamoyl-3-methoxy­imino-4-methyl­piperidine-1-carboxyl­ate
title_full_unstemmed tert-Butyl 4-carbamoyl-3-methoxy­imino-4-methyl­piperidine-1-carboxyl­ate
title_short tert-Butyl 4-carbamoyl-3-methoxy­imino-4-methyl­piperidine-1-carboxyl­ate
title_sort tert-butyl 4-carbamoyl-3-methoxy­imino-4-methyl­piperidine-1-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960090/
https://www.ncbi.nlm.nih.gov/pubmed/21581272
http://dx.doi.org/10.1107/S1600536808036106
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AT liumingliang tertbutyl4carbamoyl3methoxyimino4methylpiperidine1carboxylate
AT caojue tertbutyl4carbamoyl3methoxyimino4methylpiperidine1carboxylate
AT wangyucheng tertbutyl4carbamoyl3methoxyimino4methylpiperidine1carboxylate

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