4-(4-Fluoro­phen­yl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one

The crystal structure of the title compound, C(15)H(11)FN(2)O(3), was determined as part of a study on the biological activity of isoxazolone derivatives as p38 mitogen-activated protein kinase (MAPK) inhibitors. The dihedral angles between rings are isoxazole/benzene = 55.0 (3)°, isoxazole/pyridine...

Descripción completa

Detalles Bibliográficos
Autores principales: Margutti, Simona, Schollmeyer, Dieter, Laufer, Stefan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960186/
https://www.ncbi.nlm.nih.gov/pubmed/21201524
http://dx.doi.org/10.1107/S1600536807066500
_version_ 1782188678966149120
author Margutti, Simona
Schollmeyer, Dieter
Laufer, Stefan
author_facet Margutti, Simona
Schollmeyer, Dieter
Laufer, Stefan
author_sort Margutti, Simona
collection PubMed
description The crystal structure of the title compound, C(15)H(11)FN(2)O(3), was determined as part of a study on the biological activity of isoxazolone derivatives as p38 mitogen-activated protein kinase (MAPK) inhibitors. The dihedral angles between rings are isoxazole/benzene = 55.0 (3)°, isoxazole/pyridine = 33.8 (2)° and benzene/pyridine = 58.1 (2)°.
format Text
id pubmed-2960186
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29601862010-12-30 4-(4-Fluoro­phen­yl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one Margutti, Simona Schollmeyer, Dieter Laufer, Stefan Acta Crystallogr Sect E Struct Rep Online Organic Papers The crystal structure of the title compound, C(15)H(11)FN(2)O(3), was determined as part of a study on the biological activity of isoxazolone derivatives as p38 mitogen-activated protein kinase (MAPK) inhibitors. The dihedral angles between rings are isoxazole/benzene = 55.0 (3)°, isoxazole/pyridine = 33.8 (2)° and benzene/pyridine = 58.1 (2)°. International Union of Crystallography 2008-01-23 /pmc/articles/PMC2960186/ /pubmed/21201524 http://dx.doi.org/10.1107/S1600536807066500 Text en © International Union of Crystallography 2008 http://journals.iucr.org/services/termsofuse.html This is an open-access article distributed under the terms described at http://journals.iucr.org/services/termsofuse.html.
spellingShingle Organic Papers
Margutti, Simona
Schollmeyer, Dieter
Laufer, Stefan
4-(4-Fluoro­phen­yl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one
title 4-(4-Fluoro­phen­yl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one
title_full 4-(4-Fluoro­phen­yl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one
title_fullStr 4-(4-Fluoro­phen­yl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one
title_full_unstemmed 4-(4-Fluoro­phen­yl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one
title_short 4-(4-Fluoro­phen­yl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one
title_sort 4-(4-fluoro­phen­yl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2h)-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960186/
https://www.ncbi.nlm.nih.gov/pubmed/21201524
http://dx.doi.org/10.1107/S1600536807066500
work_keys_str_mv AT marguttisimona 44fluorophenyl2methyl31oxy4pyridylisoxazol52hone
AT schollmeyerdieter 44fluorophenyl2methyl31oxy4pyridylisoxazol52hone
AT lauferstefan 44fluorophenyl2methyl31oxy4pyridylisoxazol52hone

Ejemplares similares