1-Benzyl-2-(1H-indol-3-yl)-5-oxo­pyrrolidine-2-carbonitrile

In the title compound, C(20)H(17)N(3)O, a potential anti-human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse-transcriptase inhibitor, the pyrrolidine ring has an envelope conformation. In the crystal structure, adjacent mol­ecules are connected into infinite chains via an N—H⋯O hydrog...

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Detalles Bibliográficos
Autores principales: Tamazyan, Rafael, Armen, Ayvazyan, Ashot, Martirosyan, Sahak, Gasparyan, Schinazi, Raymond
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960201/
https://www.ncbi.nlm.nih.gov/pubmed/21201400
http://dx.doi.org/10.1107/S1600536807067670
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author Tamazyan, Rafael
Armen, Ayvazyan
Ashot, Martirosyan
Sahak, Gasparyan
Schinazi, Raymond
author_facet Tamazyan, Rafael
Armen, Ayvazyan
Ashot, Martirosyan
Sahak, Gasparyan
Schinazi, Raymond
author_sort Tamazyan, Rafael
collection PubMed
description In the title compound, C(20)H(17)N(3)O, a potential anti-human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse-transcriptase inhibitor, the pyrrolidine ring has an envelope conformation. In the crystal structure, adjacent mol­ecules are connected into infinite chains via an N—H⋯O hydrogen bond.
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spelling pubmed-29602012010-12-30 1-Benzyl-2-(1H-indol-3-yl)-5-oxo­pyrrolidine-2-carbonitrile Tamazyan, Rafael Armen, Ayvazyan Ashot, Martirosyan Sahak, Gasparyan Schinazi, Raymond Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(20)H(17)N(3)O, a potential anti-human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse-transcriptase inhibitor, the pyrrolidine ring has an envelope conformation. In the crystal structure, adjacent mol­ecules are connected into infinite chains via an N—H⋯O hydrogen bond. International Union of Crystallography 2008-01-04 /pmc/articles/PMC2960201/ /pubmed/21201400 http://dx.doi.org/10.1107/S1600536807067670 Text en © Tamazyan et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Tamazyan, Rafael
Armen, Ayvazyan
Ashot, Martirosyan
Sahak, Gasparyan
Schinazi, Raymond
1-Benzyl-2-(1H-indol-3-yl)-5-oxo­pyrrolidine-2-carbonitrile
title 1-Benzyl-2-(1H-indol-3-yl)-5-oxo­pyrrolidine-2-carbonitrile
title_full 1-Benzyl-2-(1H-indol-3-yl)-5-oxo­pyrrolidine-2-carbonitrile
title_fullStr 1-Benzyl-2-(1H-indol-3-yl)-5-oxo­pyrrolidine-2-carbonitrile
title_full_unstemmed 1-Benzyl-2-(1H-indol-3-yl)-5-oxo­pyrrolidine-2-carbonitrile
title_short 1-Benzyl-2-(1H-indol-3-yl)-5-oxo­pyrrolidine-2-carbonitrile
title_sort 1-benzyl-2-(1h-indol-3-yl)-5-oxo­pyrrolidine-2-carbonitrile
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960201/
https://www.ncbi.nlm.nih.gov/pubmed/21201400
http://dx.doi.org/10.1107/S1600536807067670
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AT sahakgasparyan 1benzyl21hindol3yl5oxopyrrolidine2carbonitrile
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