1-Methyl-2-(4-methyl­phen­yl)-4-morpholinopyridazine-3,6(1H,2H)-dione

The structure analysis of the title compound, C(16)H(19)N(3)O(3), has been undertaken in order to facilitate the inter­pretation of (1)H and (13)C NMR data and to determine the position of the morpholine residue in this nucleophilic substitution product. The main result is that the morpholine group,...

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Autores principales: Gzella, Andrzej, Melzer, Ewa, Kaczmarek, Michał S., Woźniak, Zenon
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960232/
https://www.ncbi.nlm.nih.gov/pubmed/21201462
http://dx.doi.org/10.1107/S1600536808000111
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author Gzella, Andrzej
Melzer, Ewa
Kaczmarek, Michał S.
Woźniak, Zenon
author_facet Gzella, Andrzej
Melzer, Ewa
Kaczmarek, Michał S.
Woźniak, Zenon
author_sort Gzella, Andrzej
collection PubMed
description The structure analysis of the title compound, C(16)H(19)N(3)O(3), has been undertaken in order to facilitate the inter­pretation of (1)H and (13)C NMR data and to determine the position of the morpholine residue in this nucleophilic substitution product. The main result is that the morpholine group, with a chair conformation, is connected at the 4-position of the pyridazine ring. The benzene and pyridazine rings make a dihedral angle of 62.17 (5)°. Mol­ecules are linked into a two-dimensional network by non-classical C—H⋯O hydrogen bonds, in which O atoms serve as double or triple acceptors.
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spelling pubmed-29602322010-12-30 1-Methyl-2-(4-methyl­phen­yl)-4-morpholinopyridazine-3,6(1H,2H)-dione Gzella, Andrzej Melzer, Ewa Kaczmarek, Michał S. Woźniak, Zenon Acta Crystallogr Sect E Struct Rep Online Organic Papers The structure analysis of the title compound, C(16)H(19)N(3)O(3), has been undertaken in order to facilitate the inter­pretation of (1)H and (13)C NMR data and to determine the position of the morpholine residue in this nucleophilic substitution product. The main result is that the morpholine group, with a chair conformation, is connected at the 4-position of the pyridazine ring. The benzene and pyridazine rings make a dihedral angle of 62.17 (5)°. Mol­ecules are linked into a two-dimensional network by non-classical C—H⋯O hydrogen bonds, in which O atoms serve as double or triple acceptors. International Union of Crystallography 2008-01-11 /pmc/articles/PMC2960232/ /pubmed/21201462 http://dx.doi.org/10.1107/S1600536808000111 Text en © Gzella et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Gzella, Andrzej
Melzer, Ewa
Kaczmarek, Michał S.
Woźniak, Zenon
1-Methyl-2-(4-methyl­phen­yl)-4-morpholinopyridazine-3,6(1H,2H)-dione
title 1-Methyl-2-(4-methyl­phen­yl)-4-morpholinopyridazine-3,6(1H,2H)-dione
title_full 1-Methyl-2-(4-methyl­phen­yl)-4-morpholinopyridazine-3,6(1H,2H)-dione
title_fullStr 1-Methyl-2-(4-methyl­phen­yl)-4-morpholinopyridazine-3,6(1H,2H)-dione
title_full_unstemmed 1-Methyl-2-(4-methyl­phen­yl)-4-morpholinopyridazine-3,6(1H,2H)-dione
title_short 1-Methyl-2-(4-methyl­phen­yl)-4-morpholinopyridazine-3,6(1H,2H)-dione
title_sort 1-methyl-2-(4-methyl­phen­yl)-4-morpholinopyridazine-3,6(1h,2h)-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960232/
https://www.ncbi.nlm.nih.gov/pubmed/21201462
http://dx.doi.org/10.1107/S1600536808000111
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AT melzerewa 1methyl24methylphenyl4morpholinopyridazine361h2hdione
AT kaczmarekmichałs 1methyl24methylphenyl4morpholinopyridazine361h2hdione
AT wozniakzenon 1methyl24methylphenyl4morpholinopyridazine361h2hdione

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