1-Benzyl-6-phenyl­imino-5-(pyrrol-2-yl­idene)hexa­hydro­pyrimidine-2,4-dione

In the title compound, C(21)H(20)N(4)O(2), a potential anti-human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor, the pyrrolidine ring adopts an envelope conformation, while the hydrogenated pyrimidine ring adopts a weakly expressed twist conformation. The mol­e...

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Detalles Bibliográficos
Autores principales: Tamazyan, Rafael, Ayvazyan, Armen, Martirosyan, Vahan, Avagyan, Kristine, Martirosyan, Ashot
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960353/
https://www.ncbi.nlm.nih.gov/pubmed/21201507
http://dx.doi.org/10.1107/S1600536808001384
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author Tamazyan, Rafael
Ayvazyan, Armen
Martirosyan, Vahan
Avagyan, Kristine
Martirosyan, Ashot
author_facet Tamazyan, Rafael
Ayvazyan, Armen
Martirosyan, Vahan
Avagyan, Kristine
Martirosyan, Ashot
author_sort Tamazyan, Rafael
collection PubMed
description In the title compound, C(21)H(20)N(4)O(2), a potential anti-human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor, the pyrrolidine ring adopts an envelope conformation, while the hydrogenated pyrimidine ring adopts a weakly expressed twist conformation. The mol­ecules are connected into infinite chains via N—H⋯O hydrogen bonds.
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spelling pubmed-29603532010-12-30 1-Benzyl-6-phenyl­imino-5-(pyrrol-2-yl­idene)hexa­hydro­pyrimidine-2,4-dione Tamazyan, Rafael Ayvazyan, Armen Martirosyan, Vahan Avagyan, Kristine Martirosyan, Ashot Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(21)H(20)N(4)O(2), a potential anti-human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor, the pyrrolidine ring adopts an envelope conformation, while the hydrogenated pyrimidine ring adopts a weakly expressed twist conformation. The mol­ecules are connected into infinite chains via N—H⋯O hydrogen bonds. International Union of Crystallography 2008-01-23 /pmc/articles/PMC2960353/ /pubmed/21201507 http://dx.doi.org/10.1107/S1600536808001384 Text en © Tamazyan et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Tamazyan, Rafael
Ayvazyan, Armen
Martirosyan, Vahan
Avagyan, Kristine
Martirosyan, Ashot
1-Benzyl-6-phenyl­imino-5-(pyrrol-2-yl­idene)hexa­hydro­pyrimidine-2,4-dione
title 1-Benzyl-6-phenyl­imino-5-(pyrrol-2-yl­idene)hexa­hydro­pyrimidine-2,4-dione
title_full 1-Benzyl-6-phenyl­imino-5-(pyrrol-2-yl­idene)hexa­hydro­pyrimidine-2,4-dione
title_fullStr 1-Benzyl-6-phenyl­imino-5-(pyrrol-2-yl­idene)hexa­hydro­pyrimidine-2,4-dione
title_full_unstemmed 1-Benzyl-6-phenyl­imino-5-(pyrrol-2-yl­idene)hexa­hydro­pyrimidine-2,4-dione
title_short 1-Benzyl-6-phenyl­imino-5-(pyrrol-2-yl­idene)hexa­hydro­pyrimidine-2,4-dione
title_sort 1-benzyl-6-phenyl­imino-5-(pyrrol-2-yl­idene)hexa­hydro­pyrimidine-2,4-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960353/
https://www.ncbi.nlm.nih.gov/pubmed/21201507
http://dx.doi.org/10.1107/S1600536808001384
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