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1-Benzhydryl-4-(4-chlorophenylsulfonyl)piperazine
The title compound, C(23)H(23)ClN(2)O(2)S, was synthesized by the nucleophilic substitution of 1-benzhydrylpiperazine with 4-chlorophenylsulfonyl chloride. The piperazine ring is in a chair conformation. The geometry around the S atom is that of a distorted tetrahedron. There is a large range of...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960354/ https://www.ncbi.nlm.nih.gov/pubmed/21201390 http://dx.doi.org/10.1107/S1600536807067888 |
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author | Girisha, H. R. Naveen, S. Vinaya, K. Sridhar, M. A. Shashidhara Prasad, J. Rangappa, K. S. |
author_facet | Girisha, H. R. Naveen, S. Vinaya, K. Sridhar, M. A. Shashidhara Prasad, J. Rangappa, K. S. |
author_sort | Girisha, H. R. |
collection | PubMed |
description | The title compound, C(23)H(23)ClN(2)O(2)S, was synthesized by the nucleophilic substitution of 1-benzhydrylpiperazine with 4-chlorophenylsulfonyl chloride. The piperazine ring is in a chair conformation. The geometry around the S atom is that of a distorted tetrahedron. There is a large range of bond angles around the piperazine N atoms. The dihedral angle between the least-squares plane (p1) defined by the four coplanar C atoms of the piperazine ring and the benzene ring is 81.6 (1)°. The dihedral angles between p1 and the phenyl rings are 76.2 (1) and 72.9 (2)°. The two phenyl rings make a dihedral angle of 65.9 (1)°. Intramolecular C—H⋯O hydrogen bonds are present. |
format | Text |
id | pubmed-2960354 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29603542010-12-30 1-Benzhydryl-4-(4-chlorophenylsulfonyl)piperazine Girisha, H. R. Naveen, S. Vinaya, K. Sridhar, M. A. Shashidhara Prasad, J. Rangappa, K. S. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(23)H(23)ClN(2)O(2)S, was synthesized by the nucleophilic substitution of 1-benzhydrylpiperazine with 4-chlorophenylsulfonyl chloride. The piperazine ring is in a chair conformation. The geometry around the S atom is that of a distorted tetrahedron. There is a large range of bond angles around the piperazine N atoms. The dihedral angle between the least-squares plane (p1) defined by the four coplanar C atoms of the piperazine ring and the benzene ring is 81.6 (1)°. The dihedral angles between p1 and the phenyl rings are 76.2 (1) and 72.9 (2)°. The two phenyl rings make a dihedral angle of 65.9 (1)°. Intramolecular C—H⋯O hydrogen bonds are present. International Union of Crystallography 2008-01-04 /pmc/articles/PMC2960354/ /pubmed/21201390 http://dx.doi.org/10.1107/S1600536807067888 Text en © Girisha et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Girisha, H. R. Naveen, S. Vinaya, K. Sridhar, M. A. Shashidhara Prasad, J. Rangappa, K. S. 1-Benzhydryl-4-(4-chlorophenylsulfonyl)piperazine |
title | 1-Benzhydryl-4-(4-chlorophenylsulfonyl)piperazine |
title_full | 1-Benzhydryl-4-(4-chlorophenylsulfonyl)piperazine |
title_fullStr | 1-Benzhydryl-4-(4-chlorophenylsulfonyl)piperazine |
title_full_unstemmed | 1-Benzhydryl-4-(4-chlorophenylsulfonyl)piperazine |
title_short | 1-Benzhydryl-4-(4-chlorophenylsulfonyl)piperazine |
title_sort | 1-benzhydryl-4-(4-chlorophenylsulfonyl)piperazine |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960354/ https://www.ncbi.nlm.nih.gov/pubmed/21201390 http://dx.doi.org/10.1107/S1600536807067888 |
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