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1-Benzhydryl-4-(4-chloro­phenyl­sulfonyl)piperazine

The title compound, C(23)H(23)ClN(2)O(2)S, was synthesized by the nucleophilic substitution of 1-benzhydrylpiperazine with 4-chloro­phenyl­sulfonyl chloride. The piperazine ring is in a chair conformation. The geometry around the S atom is that of a distorted tetra­hedron. There is a large range of...

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Autores principales: Girisha, H. R., Naveen, S., Vinaya, K., Sridhar, M. A., Shashidhara Prasad, J., Rangappa, K. S.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960354/
https://www.ncbi.nlm.nih.gov/pubmed/21201390
http://dx.doi.org/10.1107/S1600536807067888
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author Girisha, H. R.
Naveen, S.
Vinaya, K.
Sridhar, M. A.
Shashidhara Prasad, J.
Rangappa, K. S.
author_facet Girisha, H. R.
Naveen, S.
Vinaya, K.
Sridhar, M. A.
Shashidhara Prasad, J.
Rangappa, K. S.
author_sort Girisha, H. R.
collection PubMed
description The title compound, C(23)H(23)ClN(2)O(2)S, was synthesized by the nucleophilic substitution of 1-benzhydrylpiperazine with 4-chloro­phenyl­sulfonyl chloride. The piperazine ring is in a chair conformation. The geometry around the S atom is that of a distorted tetra­hedron. There is a large range of bond angles around the piperazine N atoms. The dihedral angle between the least-squares plane (p1) defined by the four coplanar C atoms of the piperazine ring and the benzene ring is 81.6 (1)°. The dihedral angles between p1 and the phenyl rings are 76.2 (1) and 72.9 (2)°. The two phenyl rings make a dihedral angle of 65.9 (1)°. Intramolecular C—H⋯O hydrogen bonds are present.
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spelling pubmed-29603542010-12-30 1-Benzhydryl-4-(4-chloro­phenyl­sulfonyl)piperazine Girisha, H. R. Naveen, S. Vinaya, K. Sridhar, M. A. Shashidhara Prasad, J. Rangappa, K. S. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(23)H(23)ClN(2)O(2)S, was synthesized by the nucleophilic substitution of 1-benzhydrylpiperazine with 4-chloro­phenyl­sulfonyl chloride. The piperazine ring is in a chair conformation. The geometry around the S atom is that of a distorted tetra­hedron. There is a large range of bond angles around the piperazine N atoms. The dihedral angle between the least-squares plane (p1) defined by the four coplanar C atoms of the piperazine ring and the benzene ring is 81.6 (1)°. The dihedral angles between p1 and the phenyl rings are 76.2 (1) and 72.9 (2)°. The two phenyl rings make a dihedral angle of 65.9 (1)°. Intramolecular C—H⋯O hydrogen bonds are present. International Union of Crystallography 2008-01-04 /pmc/articles/PMC2960354/ /pubmed/21201390 http://dx.doi.org/10.1107/S1600536807067888 Text en © Girisha et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Girisha, H. R.
Naveen, S.
Vinaya, K.
Sridhar, M. A.
Shashidhara Prasad, J.
Rangappa, K. S.
1-Benzhydryl-4-(4-chloro­phenyl­sulfonyl)piperazine
title 1-Benzhydryl-4-(4-chloro­phenyl­sulfonyl)piperazine
title_full 1-Benzhydryl-4-(4-chloro­phenyl­sulfonyl)piperazine
title_fullStr 1-Benzhydryl-4-(4-chloro­phenyl­sulfonyl)piperazine
title_full_unstemmed 1-Benzhydryl-4-(4-chloro­phenyl­sulfonyl)piperazine
title_short 1-Benzhydryl-4-(4-chloro­phenyl­sulfonyl)piperazine
title_sort 1-benzhydryl-4-(4-chloro­phenyl­sulfonyl)piperazine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960354/
https://www.ncbi.nlm.nih.gov/pubmed/21201390
http://dx.doi.org/10.1107/S1600536807067888
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