4-[3-(Trifluoro­meth­yl)phen­yl]-5,6,7,8-tetra­hydro­cinnolin-3(2H)-one

The title compound, C(15)H(13)F(3)N(2)O, contains one benzene ring, one cyclo­hexane ring and a pyridazine ring. The dihedral angle formed by the pyridazine ring with the benzene ring is 61.5 (2)°. The crystal structure is stabilized by two inter­molecular hydrogen bonds (N—H⋯O and C—H⋯F). The cyclo...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Zou, Xiao-Mao, Zhu, You-Quan, Hu, Xu-Hong, Yang, Hua-Zheng
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960356/
https://www.ncbi.nlm.nih.gov/pubmed/21201490
http://dx.doi.org/10.1107/S1600536808000871
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author Wang, Xin
Zou, Xiao-Mao
Zhu, You-Quan
Hu, Xu-Hong
Yang, Hua-Zheng
author_facet Wang, Xin
Zou, Xiao-Mao
Zhu, You-Quan
Hu, Xu-Hong
Yang, Hua-Zheng
author_sort Wang, Xin
collection PubMed
description The title compound, C(15)H(13)F(3)N(2)O, contains one benzene ring, one cyclo­hexane ring and a pyridazine ring. The dihedral angle formed by the pyridazine ring with the benzene ring is 61.5 (2)°. The crystal structure is stabilized by two inter­molecular hydrogen bonds (N—H⋯O and C—H⋯F). The cyclohexane ring adopts a screw-boat conformation. The CF(3) group is disordered over two positions; the site occupancy factors are ca 0.6 and 0.4.
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spelling pubmed-29603562010-12-30 4-[3-(Trifluoro­meth­yl)phen­yl]-5,6,7,8-tetra­hydro­cinnolin-3(2H)-one Wang, Xin Zou, Xiao-Mao Zhu, You-Quan Hu, Xu-Hong Yang, Hua-Zheng Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(15)H(13)F(3)N(2)O, contains one benzene ring, one cyclo­hexane ring and a pyridazine ring. The dihedral angle formed by the pyridazine ring with the benzene ring is 61.5 (2)°. The crystal structure is stabilized by two inter­molecular hydrogen bonds (N—H⋯O and C—H⋯F). The cyclohexane ring adopts a screw-boat conformation. The CF(3) group is disordered over two positions; the site occupancy factors are ca 0.6 and 0.4. International Union of Crystallography 2008-01-18 /pmc/articles/PMC2960356/ /pubmed/21201490 http://dx.doi.org/10.1107/S1600536808000871 Text en © Wang et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wang, Xin
Zou, Xiao-Mao
Zhu, You-Quan
Hu, Xu-Hong
Yang, Hua-Zheng
4-[3-(Trifluoro­meth­yl)phen­yl]-5,6,7,8-tetra­hydro­cinnolin-3(2H)-one
title 4-[3-(Trifluoro­meth­yl)phen­yl]-5,6,7,8-tetra­hydro­cinnolin-3(2H)-one
title_full 4-[3-(Trifluoro­meth­yl)phen­yl]-5,6,7,8-tetra­hydro­cinnolin-3(2H)-one
title_fullStr 4-[3-(Trifluoro­meth­yl)phen­yl]-5,6,7,8-tetra­hydro­cinnolin-3(2H)-one
title_full_unstemmed 4-[3-(Trifluoro­meth­yl)phen­yl]-5,6,7,8-tetra­hydro­cinnolin-3(2H)-one
title_short 4-[3-(Trifluoro­meth­yl)phen­yl]-5,6,7,8-tetra­hydro­cinnolin-3(2H)-one
title_sort 4-[3-(trifluoro­meth­yl)phen­yl]-5,6,7,8-tetra­hydro­cinnolin-3(2h)-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960356/
https://www.ncbi.nlm.nih.gov/pubmed/21201490
http://dx.doi.org/10.1107/S1600536808000871
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