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(4R)-4-[(1R)-1,2-Dihydroxy­ethyl]-1-[(1R)-1-phenyl­ethyl]pyrrolidin-2-one

The title compound, C(14)H(19)NO(3), was obtained as one of the two isomers of a Sharpless asymmetric dihydroxy­lation reaction of (1S)-1-[(1R)-1-phenyl­ethyl]-4-vinyl­pyrrolidin-2-one. The absolute stereochemistry of this isomer was determined from the known stereochemistry (R) at the bridge C atom...

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Detalles Bibliográficos
Autores principales: Blaser, Adrian, Boyd, Peter D. W.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960542/
https://www.ncbi.nlm.nih.gov/pubmed/21201822
http://dx.doi.org/10.1107/S1600536808027293
Descripción
Sumario:The title compound, C(14)H(19)NO(3), was obtained as one of the two isomers of a Sharpless asymmetric dihydroxy­lation reaction of (1S)-1-[(1R)-1-phenyl­ethyl]-4-vinyl­pyrrolidin-2-one. The absolute stereochemistry of this isomer was determined from the known stereochemistry (R) at the bridge C atom between the phenyl and pyrrolidine rings. The mol­ecules form one-dimensional tapes along the b axis via hydrogen bonding between the carbonyl O atom and the alcohol groups of neighbouring mol­ecules. These assemble into sheets via inter­digitative stacking of the phenyl rings and C—H⋯O inter­actions.