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3α-Azido-5-cholestene
The crystal structure of the title compound, C(27)H(45)N(3), has been determined as part of our investigation into the hydrophobic modification of aminoglycoside antibiotics. The isopropyl group showed disorder for the tertiary carbon (equal occupancies), with high thermal motion for the peripher...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960626/ https://www.ncbi.nlm.nih.gov/pubmed/21201721 http://dx.doi.org/10.1107/S1600536808025294 |
| Sumario: | The crystal structure of the title compound, C(27)H(45)N(3), has been determined as part of our investigation into the hydrophobic modification of aminoglycoside antibiotics. The isopropyl group showed disorder for the tertiary carbon (equal occupancies), with high thermal motion for the peripheral atoms of the isopropyl and azide groups also apparent in the structure. The axial disposition of the azide group is consistent with the clean inversion of stereochemistry at C-3 under Mitsunobu conditions. |
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