Ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate

The title compound, C(14)H(16)N(2)O(3), belongs to a group of esters of 2-oxo- and 1,2,3,4-tetra­hydro­pyrimidine-5-carboxylic acids, which exhibit a wide spectrum of biological activities. The dihydro­pyrimidine ring adopts a screw-boat conformation. The crystal packing is stabilized by strong N—H⋯...

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Detalles Bibliográficos
Autores principales: Nizam Mohideen, M., Rasheeth, A., Huq, C. A. M. A., Nizar, S. Syed
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960668/
https://www.ncbi.nlm.nih.gov/pubmed/21201734
http://dx.doi.org/10.1107/S1600536808025610
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author Nizam Mohideen, M.
Rasheeth, A.
Huq, C. A. M. A.
Nizar, S. Syed
author_facet Nizam Mohideen, M.
Rasheeth, A.
Huq, C. A. M. A.
Nizar, S. Syed
author_sort Nizam Mohideen, M.
collection PubMed
description The title compound, C(14)H(16)N(2)O(3), belongs to a group of esters of 2-oxo- and 1,2,3,4-tetra­hydro­pyrimidine-5-carboxylic acids, which exhibit a wide spectrum of biological activities. The dihydro­pyrimidine ring adopts a screw-boat conformation. The crystal packing is stabilized by strong N—H⋯O and weak C—H⋯O inter­molecular hydrogen bonds. An intra­molecular C—H⋯O hydrogen bond is also present.
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spelling pubmed-29606682010-12-30 Ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate Nizam Mohideen, M. Rasheeth, A. Huq, C. A. M. A. Nizar, S. Syed Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(14)H(16)N(2)O(3), belongs to a group of esters of 2-oxo- and 1,2,3,4-tetra­hydro­pyrimidine-5-carboxylic acids, which exhibit a wide spectrum of biological activities. The dihydro­pyrimidine ring adopts a screw-boat conformation. The crystal packing is stabilized by strong N—H⋯O and weak C—H⋯O inter­molecular hydrogen bonds. An intra­molecular C—H⋯O hydrogen bond is also present. International Union of Crystallography 2008-08-13 /pmc/articles/PMC2960668/ /pubmed/21201734 http://dx.doi.org/10.1107/S1600536808025610 Text en © Mohideen et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Nizam Mohideen, M.
Rasheeth, A.
Huq, C. A. M. A.
Nizar, S. Syed
Ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title Ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_full Ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_fullStr Ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_full_unstemmed Ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_short Ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_sort ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960668/
https://www.ncbi.nlm.nih.gov/pubmed/21201734
http://dx.doi.org/10.1107/S1600536808025610
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AT huqcama ethyl6methyl2oxo4phenyl1234tetrahydropyrimidine5carboxylate
AT nizarssyed ethyl6methyl2oxo4phenyl1234tetrahydropyrimidine5carboxylate

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