3-(4-Fluoro­phenyl)-1-[1′-(4-fluoro­phenyl)-2-oxo-5′,6′,7′,7a′-tetra­hydro-1H-indole-3(2H)-spiro-3′(2′H)-1H′-pyrrol­izin-2′-yl]prop-2-en-1-one

In the title compound, C(29)H(24)F(2)N(2)O(2), one of the pyrrolidine rings of the pyrrolizine system is disordered over two sites, with occupancy factors 0.734:0.266 (12). Both components of the disordered pyrrolidine ring adopt envelope conformations, whereas the other pyrrolidine ring adopts a tw...

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Autores principales: Nirmala, S., Murugan, R., Kamala, E. Theboral Sugi, Sudha, L., Sriman Narayanan, S.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960725/
https://www.ncbi.nlm.nih.gov/pubmed/21201755
http://dx.doi.org/10.1107/S1600536808025774
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author Nirmala, S.
Murugan, R.
Kamala, E. Theboral Sugi
Sudha, L.
Sriman Narayanan, S.
author_facet Nirmala, S.
Murugan, R.
Kamala, E. Theboral Sugi
Sudha, L.
Sriman Narayanan, S.
author_sort Nirmala, S.
collection PubMed
description In the title compound, C(29)H(24)F(2)N(2)O(2), one of the pyrrolidine rings of the pyrrolizine system is disordered over two sites, with occupancy factors 0.734:0.266 (12). Both components of the disordered pyrrolidine ring adopt envelope conformations, whereas the other pyrrolidine ring adopts a twist conformation. The mol­ecules are linked into centrosymmetric dimers by N—H⋯O hydrogen bonds and the dimers are connected via C—H⋯π inter­actions. The crystal structure is also stabilized by inter­molecular C—H⋯F hydrogen bonds.
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spelling pubmed-29607252010-12-30 3-(4-Fluoro­phenyl)-1-[1′-(4-fluoro­phenyl)-2-oxo-5′,6′,7′,7a′-tetra­hydro-1H-indole-3(2H)-spiro-3′(2′H)-1H′-pyrrol­izin-2′-yl]prop-2-en-1-one Nirmala, S. Murugan, R. Kamala, E. Theboral Sugi Sudha, L. Sriman Narayanan, S. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(29)H(24)F(2)N(2)O(2), one of the pyrrolidine rings of the pyrrolizine system is disordered over two sites, with occupancy factors 0.734:0.266 (12). Both components of the disordered pyrrolidine ring adopt envelope conformations, whereas the other pyrrolidine ring adopts a twist conformation. The mol­ecules are linked into centrosymmetric dimers by N—H⋯O hydrogen bonds and the dimers are connected via C—H⋯π inter­actions. The crystal structure is also stabilized by inter­molecular C—H⋯F hydrogen bonds. International Union of Crystallography 2008-08-16 /pmc/articles/PMC2960725/ /pubmed/21201755 http://dx.doi.org/10.1107/S1600536808025774 Text en © Nirmala et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Nirmala, S.
Murugan, R.
Kamala, E. Theboral Sugi
Sudha, L.
Sriman Narayanan, S.
3-(4-Fluoro­phenyl)-1-[1′-(4-fluoro­phenyl)-2-oxo-5′,6′,7′,7a′-tetra­hydro-1H-indole-3(2H)-spiro-3′(2′H)-1H′-pyrrol­izin-2′-yl]prop-2-en-1-one
title 3-(4-Fluoro­phenyl)-1-[1′-(4-fluoro­phenyl)-2-oxo-5′,6′,7′,7a′-tetra­hydro-1H-indole-3(2H)-spiro-3′(2′H)-1H′-pyrrol­izin-2′-yl]prop-2-en-1-one
title_full 3-(4-Fluoro­phenyl)-1-[1′-(4-fluoro­phenyl)-2-oxo-5′,6′,7′,7a′-tetra­hydro-1H-indole-3(2H)-spiro-3′(2′H)-1H′-pyrrol­izin-2′-yl]prop-2-en-1-one
title_fullStr 3-(4-Fluoro­phenyl)-1-[1′-(4-fluoro­phenyl)-2-oxo-5′,6′,7′,7a′-tetra­hydro-1H-indole-3(2H)-spiro-3′(2′H)-1H′-pyrrol­izin-2′-yl]prop-2-en-1-one
title_full_unstemmed 3-(4-Fluoro­phenyl)-1-[1′-(4-fluoro­phenyl)-2-oxo-5′,6′,7′,7a′-tetra­hydro-1H-indole-3(2H)-spiro-3′(2′H)-1H′-pyrrol­izin-2′-yl]prop-2-en-1-one
title_short 3-(4-Fluoro­phenyl)-1-[1′-(4-fluoro­phenyl)-2-oxo-5′,6′,7′,7a′-tetra­hydro-1H-indole-3(2H)-spiro-3′(2′H)-1H′-pyrrol­izin-2′-yl]prop-2-en-1-one
title_sort 3-(4-fluoro­phenyl)-1-[1′-(4-fluoro­phenyl)-2-oxo-5′,6′,7′,7a′-tetra­hydro-1h-indole-3(2h)-spiro-3′(2′h)-1h′-pyrrol­izin-2′-yl]prop-2-en-1-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960725/
https://www.ncbi.nlm.nih.gov/pubmed/21201755
http://dx.doi.org/10.1107/S1600536808025774
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