N-(Hydroxymethyl)ibogaine

The title compound (systematic name: 16-hydroxy­methyl-12-methoxy­ibogamine), C(21)H(28)N(2)O(2), was prepared by reaction of ibogaine with a formaldehyde–acetic acid solution (pH = 4). The crystal structure of this new product, belonging to the iboga indole family, is stabilized by an inter­molecul...

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Detalles Bibliográficos
Autores principales: Jarraya, Raoudha Mezghani, Bouaziz, Amira, Hamdi, Besma, Ben Salah, Abdelhamid, Damak, Mohamed
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960727/
https://www.ncbi.nlm.nih.gov/pubmed/21201722
http://dx.doi.org/10.1107/S1600536808025324
Descripción
Sumario:The title compound (systematic name: 16-hydroxy­methyl-12-methoxy­ibogamine), C(21)H(28)N(2)O(2), was prepared by reaction of ibogaine with a formaldehyde–acetic acid solution (pH = 4). The crystal structure of this new product, belonging to the iboga indole family, is stabilized by an inter­molecular O—H⋯N hydrogen bond. The identity of the compound was confirmed by one- and two-dimensional NMR spectroscopic techniques.

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