N-(Hydroxymethyl)ibogaine

The title compound (systematic name: 16-hydroxy­methyl-12-methoxy­ibogamine), C(21)H(28)N(2)O(2), was prepared by reaction of ibogaine with a formaldehyde–acetic acid solution (pH = 4). The crystal structure of this new product, belonging to the iboga indole family, is stabilized by an inter­molecul...

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Detalles Bibliográficos
Autores principales: Jarraya, Raoudha Mezghani, Bouaziz, Amira, Hamdi, Besma, Ben Salah, Abdelhamid, Damak, Mohamed
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960727/
https://www.ncbi.nlm.nih.gov/pubmed/21201722
http://dx.doi.org/10.1107/S1600536808025324
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author Jarraya, Raoudha Mezghani
Bouaziz, Amira
Hamdi, Besma
Ben Salah, Abdelhamid
Damak, Mohamed
author_facet Jarraya, Raoudha Mezghani
Bouaziz, Amira
Hamdi, Besma
Ben Salah, Abdelhamid
Damak, Mohamed
author_sort Jarraya, Raoudha Mezghani
collection PubMed
description The title compound (systematic name: 16-hydroxy­methyl-12-methoxy­ibogamine), C(21)H(28)N(2)O(2), was prepared by reaction of ibogaine with a formaldehyde–acetic acid solution (pH = 4). The crystal structure of this new product, belonging to the iboga indole family, is stabilized by an inter­molecular O—H⋯N hydrogen bond. The identity of the compound was confirmed by one- and two-dimensional NMR spectroscopic techniques.
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spelling pubmed-29607272010-12-30 N-(Hydroxymethyl)ibogaine Jarraya, Raoudha Mezghani Bouaziz, Amira Hamdi, Besma Ben Salah, Abdelhamid Damak, Mohamed Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound (systematic name: 16-hydroxy­methyl-12-methoxy­ibogamine), C(21)H(28)N(2)O(2), was prepared by reaction of ibogaine with a formaldehyde–acetic acid solution (pH = 4). The crystal structure of this new product, belonging to the iboga indole family, is stabilized by an inter­molecular O—H⋯N hydrogen bond. The identity of the compound was confirmed by one- and two-dimensional NMR spectroscopic techniques. International Union of Crystallography 2008-08-09 /pmc/articles/PMC2960727/ /pubmed/21201722 http://dx.doi.org/10.1107/S1600536808025324 Text en © Jarraya et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Jarraya, Raoudha Mezghani
Bouaziz, Amira
Hamdi, Besma
Ben Salah, Abdelhamid
Damak, Mohamed
N-(Hydroxymethyl)ibogaine
title N-(Hydroxymethyl)ibogaine
title_full N-(Hydroxymethyl)ibogaine
title_fullStr N-(Hydroxymethyl)ibogaine
title_full_unstemmed N-(Hydroxymethyl)ibogaine
title_short N-(Hydroxymethyl)ibogaine
title_sort n-(hydroxymethyl)ibogaine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960727/
https://www.ncbi.nlm.nih.gov/pubmed/21201722
http://dx.doi.org/10.1107/S1600536808025324
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AT bouazizamira nhydroxymethylibogaine
AT hamdibesma nhydroxymethylibogaine
AT bensalahabdelhamid nhydroxymethylibogaine
AT damakmohamed nhydroxymethylibogaine

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