(11R,13R)-13-(Tetra­lin-1-ylamino)-4,5-ep­oxy-11,13-dihydro­costunolide

The title compound [systematic name: (12R)-4,8-dimethyl-12-[(1′R)-1′,2′,3′,4′-tetrahydro-1′-naphthyl)aminomethyl]-3,14-dioxatricyclo[9.3.0.0(2,4)]tetradec-7-en-13-one}, C(25)H(33)NO(3), was formed from the reaction of (1R)-1-amino­tetra­lin with parthenolide in methano­lic solution. X-ray crystal st...

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Detalles Bibliográficos
Autores principales: Nasim, Shama, Parkin, Sean, Crooks, Peter A.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960798/
https://www.ncbi.nlm.nih.gov/pubmed/21201970
http://dx.doi.org/10.1107/S1600536808003322
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author Nasim, Shama
Parkin, Sean
Crooks, Peter A.
author_facet Nasim, Shama
Parkin, Sean
Crooks, Peter A.
author_sort Nasim, Shama
collection PubMed
description The title compound [systematic name: (12R)-4,8-dimethyl-12-[(1′R)-1′,2′,3′,4′-tetrahydro-1′-naphthyl)aminomethyl]-3,14-dioxatricyclo[9.3.0.0(2,4)]tetradec-7-en-13-one}, C(25)H(33)NO(3), was formed from the reaction of (1R)-1-amino­tetra­lin with parthenolide in methano­lic solution. X-ray crystal structure analysis determined that the configuration of the new chiral center in the title compound was R.
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spelling pubmed-29607982010-12-30 (11R,13R)-13-(Tetra­lin-1-ylamino)-4,5-ep­oxy-11,13-dihydro­costunolide Nasim, Shama Parkin, Sean Crooks, Peter A. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound [systematic name: (12R)-4,8-dimethyl-12-[(1′R)-1′,2′,3′,4′-tetrahydro-1′-naphthyl)aminomethyl]-3,14-dioxatricyclo[9.3.0.0(2,4)]tetradec-7-en-13-one}, C(25)H(33)NO(3), was formed from the reaction of (1R)-1-amino­tetra­lin with parthenolide in methano­lic solution. X-ray crystal structure analysis determined that the configuration of the new chiral center in the title compound was R. International Union of Crystallography 2008-02-29 /pmc/articles/PMC2960798/ /pubmed/21201970 http://dx.doi.org/10.1107/S1600536808003322 Text en © Nasim et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Nasim, Shama
Parkin, Sean
Crooks, Peter A.
(11R,13R)-13-(Tetra­lin-1-ylamino)-4,5-ep­oxy-11,13-dihydro­costunolide
title (11R,13R)-13-(Tetra­lin-1-ylamino)-4,5-ep­oxy-11,13-dihydro­costunolide
title_full (11R,13R)-13-(Tetra­lin-1-ylamino)-4,5-ep­oxy-11,13-dihydro­costunolide
title_fullStr (11R,13R)-13-(Tetra­lin-1-ylamino)-4,5-ep­oxy-11,13-dihydro­costunolide
title_full_unstemmed (11R,13R)-13-(Tetra­lin-1-ylamino)-4,5-ep­oxy-11,13-dihydro­costunolide
title_short (11R,13R)-13-(Tetra­lin-1-ylamino)-4,5-ep­oxy-11,13-dihydro­costunolide
title_sort (11r,13r)-13-(tetra­lin-1-ylamino)-4,5-ep­oxy-11,13-dihydro­costunolide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960798/
https://www.ncbi.nlm.nih.gov/pubmed/21201970
http://dx.doi.org/10.1107/S1600536808003322
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AT parkinsean 11r13r13tetralin1ylamino45epoxy1113dihydrocostunolide
AT crookspetera 11r13r13tetralin1ylamino45epoxy1113dihydrocostunolide

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