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1-(4-Bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide
In the title compound, C(18)H(17)BrN(2)O(2), which is a potential human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor, the pyrrolidine ring exhibits an envelope conformation. In the crystal structure, intermolecular N—H⋯O hydrogen bonds [N⋯O = 2.861 (3) Å] li...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960799/ https://www.ncbi.nlm.nih.gov/pubmed/21201919 http://dx.doi.org/10.1107/S1600536808003954 |
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author | Tamazyan, Rafael Ayvazyan, Armen Martirosyan, Ashot Harutunyan, Gohar Martirosyan, Vahan |
author_facet | Tamazyan, Rafael Ayvazyan, Armen Martirosyan, Ashot Harutunyan, Gohar Martirosyan, Vahan |
author_sort | Tamazyan, Rafael |
collection | PubMed |
description | In the title compound, C(18)H(17)BrN(2)O(2), which is a potential human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor, the pyrrolidine ring exhibits an envelope conformation. In the crystal structure, intermolecular N—H⋯O hydrogen bonds [N⋯O = 2.861 (3) Å] link the molecules into centrosymmetric dimers. |
format | Text |
id | pubmed-2960799 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29607992010-12-30 1-(4-Bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide Tamazyan, Rafael Ayvazyan, Armen Martirosyan, Ashot Harutunyan, Gohar Martirosyan, Vahan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(18)H(17)BrN(2)O(2), which is a potential human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor, the pyrrolidine ring exhibits an envelope conformation. In the crystal structure, intermolecular N—H⋯O hydrogen bonds [N⋯O = 2.861 (3) Å] link the molecules into centrosymmetric dimers. International Union of Crystallography 2008-02-13 /pmc/articles/PMC2960799/ /pubmed/21201919 http://dx.doi.org/10.1107/S1600536808003954 Text en © Tamazyan et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Tamazyan, Rafael Ayvazyan, Armen Martirosyan, Ashot Harutunyan, Gohar Martirosyan, Vahan 1-(4-Bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide |
title | 1-(4-Bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide |
title_full | 1-(4-Bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide |
title_fullStr | 1-(4-Bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide |
title_full_unstemmed | 1-(4-Bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide |
title_short | 1-(4-Bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide |
title_sort | 1-(4-bromobenzoyl)-2-phenylpyrrolidine-2-carboxamide |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960799/ https://www.ncbi.nlm.nih.gov/pubmed/21201919 http://dx.doi.org/10.1107/S1600536808003954 |
work_keys_str_mv | AT tamazyanrafael 14bromobenzoyl2phenylpyrrolidine2carboxamide AT ayvazyanarmen 14bromobenzoyl2phenylpyrrolidine2carboxamide AT martirosyanashot 14bromobenzoyl2phenylpyrrolidine2carboxamide AT harutunyangohar 14bromobenzoyl2phenylpyrrolidine2carboxamide AT martirosyanvahan 14bromobenzoyl2phenylpyrrolidine2carboxamide |