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1-(4-Bromo­benzo­yl)-2-phenyl­pyrrolidine-2-carboxamide

In the title compound, C(18)H(17)BrN(2)O(2), which is a potential ­human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor, the pyrrolidine ring exhibits an envelope conformation. In the crystal structure, inter­molecular N—H⋯O hydrogen bonds [N⋯O = 2.861 (3) Å] li...

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Autores principales: Tamazyan, Rafael, Ayvazyan, Armen, Martirosyan, Ashot, Harutunyan, Gohar, Martirosyan, Vahan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960799/
https://www.ncbi.nlm.nih.gov/pubmed/21201919
http://dx.doi.org/10.1107/S1600536808003954
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author Tamazyan, Rafael
Ayvazyan, Armen
Martirosyan, Ashot
Harutunyan, Gohar
Martirosyan, Vahan
author_facet Tamazyan, Rafael
Ayvazyan, Armen
Martirosyan, Ashot
Harutunyan, Gohar
Martirosyan, Vahan
author_sort Tamazyan, Rafael
collection PubMed
description In the title compound, C(18)H(17)BrN(2)O(2), which is a potential ­human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor, the pyrrolidine ring exhibits an envelope conformation. In the crystal structure, inter­molecular N—H⋯O hydrogen bonds [N⋯O = 2.861 (3) Å] link the mol­ecules into centrosymmetric dimers.
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spelling pubmed-29607992010-12-30 1-(4-Bromo­benzo­yl)-2-phenyl­pyrrolidine-2-carboxamide Tamazyan, Rafael Ayvazyan, Armen Martirosyan, Ashot Harutunyan, Gohar Martirosyan, Vahan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(18)H(17)BrN(2)O(2), which is a potential ­human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor, the pyrrolidine ring exhibits an envelope conformation. In the crystal structure, inter­molecular N—H⋯O hydrogen bonds [N⋯O = 2.861 (3) Å] link the mol­ecules into centrosymmetric dimers. International Union of Crystallography 2008-02-13 /pmc/articles/PMC2960799/ /pubmed/21201919 http://dx.doi.org/10.1107/S1600536808003954 Text en © Tamazyan et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Tamazyan, Rafael
Ayvazyan, Armen
Martirosyan, Ashot
Harutunyan, Gohar
Martirosyan, Vahan
1-(4-Bromo­benzo­yl)-2-phenyl­pyrrolidine-2-carboxamide
title 1-(4-Bromo­benzo­yl)-2-phenyl­pyrrolidine-2-carboxamide
title_full 1-(4-Bromo­benzo­yl)-2-phenyl­pyrrolidine-2-carboxamide
title_fullStr 1-(4-Bromo­benzo­yl)-2-phenyl­pyrrolidine-2-carboxamide
title_full_unstemmed 1-(4-Bromo­benzo­yl)-2-phenyl­pyrrolidine-2-carboxamide
title_short 1-(4-Bromo­benzo­yl)-2-phenyl­pyrrolidine-2-carboxamide
title_sort 1-(4-bromo­benzo­yl)-2-phenyl­pyrrolidine-2-carboxamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960799/
https://www.ncbi.nlm.nih.gov/pubmed/21201919
http://dx.doi.org/10.1107/S1600536808003954
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