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N,N-Dimethyl-3-(1-naphth­yloxy)-3-(2-thien­yl)propan-1-amine

The title compound, C(19)H(21)NOS, is an inter­mediate for the synthesis of duloxetine hydro­chloride. In the mol­ecular structure, the thio­phene and naphthalene ring systems make a dihedral angle of 87.5°. All bond lengths and angles involving heteroatoms are as expected. In the crystal structure,...

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Detalles Bibliográficos
Autores principales: Tao, Xiao, Zhang, Xiao-Qing, Yuan, Lin, Wang, Jin-Tang
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960821/
https://www.ncbi.nlm.nih.gov/pubmed/21201896
http://dx.doi.org/10.1107/S1600536808003255
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author Tao, Xiao
Zhang, Xiao-Qing
Yuan, Lin
Wang, Jin-Tang
author_facet Tao, Xiao
Zhang, Xiao-Qing
Yuan, Lin
Wang, Jin-Tang
author_sort Tao, Xiao
collection PubMed
description The title compound, C(19)H(21)NOS, is an inter­mediate for the synthesis of duloxetine hydro­chloride. In the mol­ecular structure, the thio­phene and naphthalene ring systems make a dihedral angle of 87.5°. All bond lengths and angles involving heteroatoms are as expected. In the crystal structure, no classical hydrogen bonds are found.
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spelling pubmed-29608212010-12-30 N,N-Dimethyl-3-(1-naphth­yloxy)-3-(2-thien­yl)propan-1-amine Tao, Xiao Zhang, Xiao-Qing Yuan, Lin Wang, Jin-Tang Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(19)H(21)NOS, is an inter­mediate for the synthesis of duloxetine hydro­chloride. In the mol­ecular structure, the thio­phene and naphthalene ring systems make a dihedral angle of 87.5°. All bond lengths and angles involving heteroatoms are as expected. In the crystal structure, no classical hydrogen bonds are found. International Union of Crystallography 2008-02-06 /pmc/articles/PMC2960821/ /pubmed/21201896 http://dx.doi.org/10.1107/S1600536808003255 Text en © Tao et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Tao, Xiao
Zhang, Xiao-Qing
Yuan, Lin
Wang, Jin-Tang
N,N-Dimethyl-3-(1-naphth­yloxy)-3-(2-thien­yl)propan-1-amine
title N,N-Dimethyl-3-(1-naphth­yloxy)-3-(2-thien­yl)propan-1-amine
title_full N,N-Dimethyl-3-(1-naphth­yloxy)-3-(2-thien­yl)propan-1-amine
title_fullStr N,N-Dimethyl-3-(1-naphth­yloxy)-3-(2-thien­yl)propan-1-amine
title_full_unstemmed N,N-Dimethyl-3-(1-naphth­yloxy)-3-(2-thien­yl)propan-1-amine
title_short N,N-Dimethyl-3-(1-naphth­yloxy)-3-(2-thien­yl)propan-1-amine
title_sort n,n-dimethyl-3-(1-naphth­yloxy)-3-(2-thien­yl)propan-1-amine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960821/
https://www.ncbi.nlm.nih.gov/pubmed/21201896
http://dx.doi.org/10.1107/S1600536808003255
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