Trichodermin (4β-acet­oxy-12,13-epoxy­trichothec-9-ene)

In the title natural product, C(17)H(24)O(4), which is a very potent inhibitor of protein synthesis in mammalian cells, the five-membered ring displays an envelope conformation, whereas the two six-membered rings show different conformations, viz. chair and half-chair.

Detalles Bibliográficos
Autores principales: Chen, Shao-Yuan, Zhang, Chu-Long, Chen, Yu-Zhe, Lin, Fu-Cheng
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960951/
https://www.ncbi.nlm.nih.gov/pubmed/21202093
http://dx.doi.org/10.1107/S1600536808006168
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author Chen, Shao-Yuan
Zhang, Chu-Long
Chen, Yu-Zhe
Lin, Fu-Cheng
author_facet Chen, Shao-Yuan
Zhang, Chu-Long
Chen, Yu-Zhe
Lin, Fu-Cheng
author_sort Chen, Shao-Yuan
collection PubMed
description In the title natural product, C(17)H(24)O(4), which is a very potent inhibitor of protein synthesis in mammalian cells, the five-membered ring displays an envelope conformation, whereas the two six-membered rings show different conformations, viz. chair and half-chair.
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spelling pubmed-29609512010-12-30 Trichodermin (4β-acet­oxy-12,13-epoxy­trichothec-9-ene) Chen, Shao-Yuan Zhang, Chu-Long Chen, Yu-Zhe Lin, Fu-Cheng Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title natural product, C(17)H(24)O(4), which is a very potent inhibitor of protein synthesis in mammalian cells, the five-membered ring displays an envelope conformation, whereas the two six-membered rings show different conformations, viz. chair and half-chair. International Union of Crystallography 2008-03-12 /pmc/articles/PMC2960951/ /pubmed/21202093 http://dx.doi.org/10.1107/S1600536808006168 Text en © Chen et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Chen, Shao-Yuan
Zhang, Chu-Long
Chen, Yu-Zhe
Lin, Fu-Cheng
Trichodermin (4β-acet­oxy-12,13-epoxy­trichothec-9-ene)
title Trichodermin (4β-acet­oxy-12,13-epoxy­trichothec-9-ene)
title_full Trichodermin (4β-acet­oxy-12,13-epoxy­trichothec-9-ene)
title_fullStr Trichodermin (4β-acet­oxy-12,13-epoxy­trichothec-9-ene)
title_full_unstemmed Trichodermin (4β-acet­oxy-12,13-epoxy­trichothec-9-ene)
title_short Trichodermin (4β-acet­oxy-12,13-epoxy­trichothec-9-ene)
title_sort trichodermin (4β-acet­oxy-12,13-epoxy­trichothec-9-ene)
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960951/
https://www.ncbi.nlm.nih.gov/pubmed/21202093
http://dx.doi.org/10.1107/S1600536808006168
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AT zhangchulong trichodermin4bacetoxy1213epoxytrichothec9ene
AT chenyuzhe trichodermin4bacetoxy1213epoxytrichothec9ene
AT linfucheng trichodermin4bacetoxy1213epoxytrichothec9ene

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