1-Benzyl-3-(2-furylmeth­yl)-1,2,3,4,5,6-hexa­hydro­spiro­[benzo[h]quinazoline-5,1′-cyclo­hexa­ne]-2,4-dione

The title compound, C(29)H(28)N(2)O(3), displays anti­depressant and anti­cancer activities. The furan ring is disordered over two orientations [site occupancies 0.690 (12)/0.310 (12)] related by a rotation of 180°. The ring conformations are chair for the cyclo­hexane ring, boat for the cyclo­hexa­...

Descripción completa

Detalles Bibliográficos
Autores principales: Tamazyan, Rafael, Ayvazyan, Armen, Markosyan, Ashot, Gabrielyan, Siranush
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961069/
https://www.ncbi.nlm.nih.gov/pubmed/21202138
http://dx.doi.org/10.1107/S1600536808007502
Descripción
Sumario:The title compound, C(29)H(28)N(2)O(3), displays anti­depressant and anti­cancer activities. The furan ring is disordered over two orientations [site occupancies 0.690 (12)/0.310 (12)] related by a rotation of 180°. The ring conformations are chair for the cyclo­hexane ring, boat for the cyclo­hexa­diene ring and twist for the pyrimidine ring. The crystal packing is determined solely by van der Waals inter­actions.

Ejemplares similares