1-Benzyl-3-(2-furylmeth­yl)-1,2,3,4,5,6-hexa­hydro­spiro­[benzo[h]quinazoline-5,1′-cyclo­hexa­ne]-2,4-dione

The title compound, C(29)H(28)N(2)O(3), displays anti­depressant and anti­cancer activities. The furan ring is disordered over two orientations [site occupancies 0.690 (12)/0.310 (12)] related by a rotation of 180°. The ring conformations are chair for the cyclo­hexane ring, boat for the cyclo­hexa­...

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Detalles Bibliográficos
Autores principales: Tamazyan, Rafael, Ayvazyan, Armen, Markosyan, Ashot, Gabrielyan, Siranush
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961069/
https://www.ncbi.nlm.nih.gov/pubmed/21202138
http://dx.doi.org/10.1107/S1600536808007502
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author Tamazyan, Rafael
Ayvazyan, Armen
Markosyan, Ashot
Gabrielyan, Siranush
author_facet Tamazyan, Rafael
Ayvazyan, Armen
Markosyan, Ashot
Gabrielyan, Siranush
author_sort Tamazyan, Rafael
collection PubMed
description The title compound, C(29)H(28)N(2)O(3), displays anti­depressant and anti­cancer activities. The furan ring is disordered over two orientations [site occupancies 0.690 (12)/0.310 (12)] related by a rotation of 180°. The ring conformations are chair for the cyclo­hexane ring, boat for the cyclo­hexa­diene ring and twist for the pyrimidine ring. The crystal packing is determined solely by van der Waals inter­actions.
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spelling pubmed-29610692010-12-30 1-Benzyl-3-(2-furylmeth­yl)-1,2,3,4,5,6-hexa­hydro­spiro­[benzo[h]quinazoline-5,1′-cyclo­hexa­ne]-2,4-dione Tamazyan, Rafael Ayvazyan, Armen Markosyan, Ashot Gabrielyan, Siranush Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(29)H(28)N(2)O(3), displays anti­depressant and anti­cancer activities. The furan ring is disordered over two orientations [site occupancies 0.690 (12)/0.310 (12)] related by a rotation of 180°. The ring conformations are chair for the cyclo­hexane ring, boat for the cyclo­hexa­diene ring and twist for the pyrimidine ring. The crystal packing is determined solely by van der Waals inter­actions. International Union of Crystallography 2008-03-29 /pmc/articles/PMC2961069/ /pubmed/21202138 http://dx.doi.org/10.1107/S1600536808007502 Text en © Tamazyan et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Tamazyan, Rafael
Ayvazyan, Armen
Markosyan, Ashot
Gabrielyan, Siranush
1-Benzyl-3-(2-furylmeth­yl)-1,2,3,4,5,6-hexa­hydro­spiro­[benzo[h]quinazoline-5,1′-cyclo­hexa­ne]-2,4-dione
title 1-Benzyl-3-(2-furylmeth­yl)-1,2,3,4,5,6-hexa­hydro­spiro­[benzo[h]quinazoline-5,1′-cyclo­hexa­ne]-2,4-dione
title_full 1-Benzyl-3-(2-furylmeth­yl)-1,2,3,4,5,6-hexa­hydro­spiro­[benzo[h]quinazoline-5,1′-cyclo­hexa­ne]-2,4-dione
title_fullStr 1-Benzyl-3-(2-furylmeth­yl)-1,2,3,4,5,6-hexa­hydro­spiro­[benzo[h]quinazoline-5,1′-cyclo­hexa­ne]-2,4-dione
title_full_unstemmed 1-Benzyl-3-(2-furylmeth­yl)-1,2,3,4,5,6-hexa­hydro­spiro­[benzo[h]quinazoline-5,1′-cyclo­hexa­ne]-2,4-dione
title_short 1-Benzyl-3-(2-furylmeth­yl)-1,2,3,4,5,6-hexa­hydro­spiro­[benzo[h]quinazoline-5,1′-cyclo­hexa­ne]-2,4-dione
title_sort 1-benzyl-3-(2-furylmeth­yl)-1,2,3,4,5,6-hexa­hydro­spiro­[benzo[h]quinazoline-5,1′-cyclo­hexa­ne]-2,4-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961069/
https://www.ncbi.nlm.nih.gov/pubmed/21202138
http://dx.doi.org/10.1107/S1600536808007502
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