Ethyl 4-hydroxy­methyl-2-methyl­pyridine-5-carboxyl­ate

The title compound, C(10)H(13)NO(3), was obtained as a by-product of the aldolization reaction of furo[3,4-c]pyridin-3(1H)-one with thio­phene-2-carboxaldehyde. The substituents on the pyridine ring are nearly coplanar, with an 8.1 (2)° rotation of the hydroxmethyl group from this plane. The mol­ecu...

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Detalles Bibliográficos
Autores principales: Boyd, Peter D. W., Lena, Gersande, Spicer, Julie A.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961239/
https://www.ncbi.nlm.nih.gov/pubmed/21202367
http://dx.doi.org/10.1107/S160053680801026X
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author Boyd, Peter D. W.
Lena, Gersande
Spicer, Julie A.
author_facet Boyd, Peter D. W.
Lena, Gersande
Spicer, Julie A.
author_sort Boyd, Peter D. W.
collection PubMed
description The title compound, C(10)H(13)NO(3), was obtained as a by-product of the aldolization reaction of furo[3,4-c]pyridin-3(1H)-one with thio­phene-2-carboxaldehyde. The substituents on the pyridine ring are nearly coplanar, with an 8.1 (2)° rotation of the hydroxmethyl group from this plane. The mol­ecules assemble in the crystal structure as chains via O—H⋯N hydrogen bonding between the pyridine N atom and a neighbouring hydroxy­methyl OH group.
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spelling pubmed-29612392010-12-30 Ethyl 4-hydroxy­methyl-2-methyl­pyridine-5-carboxyl­ate Boyd, Peter D. W. Lena, Gersande Spicer, Julie A. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(10)H(13)NO(3), was obtained as a by-product of the aldolization reaction of furo[3,4-c]pyridin-3(1H)-one with thio­phene-2-carboxaldehyde. The substituents on the pyridine ring are nearly coplanar, with an 8.1 (2)° rotation of the hydroxmethyl group from this plane. The mol­ecules assemble in the crystal structure as chains via O—H⋯N hydrogen bonding between the pyridine N atom and a neighbouring hydroxy­methyl OH group. International Union of Crystallography 2008-04-23 /pmc/articles/PMC2961239/ /pubmed/21202367 http://dx.doi.org/10.1107/S160053680801026X Text en © Boyd et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Boyd, Peter D. W.
Lena, Gersande
Spicer, Julie A.
Ethyl 4-hydroxy­methyl-2-methyl­pyridine-5-carboxyl­ate
title Ethyl 4-hydroxy­methyl-2-methyl­pyridine-5-carboxyl­ate
title_full Ethyl 4-hydroxy­methyl-2-methyl­pyridine-5-carboxyl­ate
title_fullStr Ethyl 4-hydroxy­methyl-2-methyl­pyridine-5-carboxyl­ate
title_full_unstemmed Ethyl 4-hydroxy­methyl-2-methyl­pyridine-5-carboxyl­ate
title_short Ethyl 4-hydroxy­methyl-2-methyl­pyridine-5-carboxyl­ate
title_sort ethyl 4-hydroxy­methyl-2-methyl­pyridine-5-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961239/
https://www.ncbi.nlm.nih.gov/pubmed/21202367
http://dx.doi.org/10.1107/S160053680801026X
work_keys_str_mv AT boydpeterdw ethyl4hydroxymethyl2methylpyridine5carboxylate
AT lenagersande ethyl4hydroxymethyl2methylpyridine5carboxylate
AT spicerjuliea ethyl4hydroxymethyl2methylpyridine5carboxylate

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