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Methyl 3-(2-chlorophenyl)-2-(1H-indol-3-ylmethyl)-5-[1-(4-methoxyphenyl)-4-oxo-3-phenylazetidin-2-yl]-4-nitropyr­rolidine-2-carboxylate

In the mol­ecule of the title compound, C(37)H(33)ClN(4)O(6), the four-membered β-lactam ring is essentially planar and is oriented at dihedral angles of 30.0 (1), 76.3 (1) and 30.9 (1)° with respect to the methoxy­phenyl ring, the phenyl ring and the indole unit, respectively. The pyrrolidine ring...

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Detalles Bibliográficos
Autores principales: Nirmala, S., Kamala, E. Theboral Sugi, Sudha, L., Arumugam, N., Raghunathan, R.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961341/
https://www.ncbi.nlm.nih.gov/pubmed/21202589
http://dx.doi.org/10.1107/S1600536808013585
Descripción
Sumario:In the mol­ecule of the title compound, C(37)H(33)ClN(4)O(6), the four-membered β-lactam ring is essentially planar and is oriented at dihedral angles of 30.0 (1), 76.3 (1) and 30.9 (1)° with respect to the methoxy­phenyl ring, the phenyl ring and the indole unit, respectively. The pyrrolidine ring adopts a twist conformation. Intra­molecular C—H⋯Cl and C—H⋯O hydrogen bonds result in the formation of two five- and one six-membered rings. In the crystal structure, inter­molecular C—H⋯O and N—H⋯O hydrogen bonds link the mol­ecules. A weak π⋯π inter­action between the pyrrole rings further stabilizes the structure, with a centroid–centroid distance of 3.806 (2) Å.