Methyl 3-(4-bromo­phen­yl)-2-(1H-indol-3-ylmeth­yl)-5-[1-(4-methoxy­phen­yl)-4-oxo-2-phenyl­azetidin-2-yl]-4-nitro­pyrrolidine-2-carboxyl­ate

In the title compound, C(37)H(33)BrN(4)O(6), the pyrrolidine ring adopts an envelope conformation. The β-lactam ring is planar and makes dihedral angles of 70.16 (13) and 28.32 (13)° with the phenyl and 4-methoxy­phenyl rings, respectively. The mol­ecular packing is stabilized by intra­molecular C—H...

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Detalles Bibliográficos
Autores principales: Nirmala, S., Kamala, E. Theboral Sugi, Sudha, L., Arumugam, N., Raghunathan, R.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961354/
https://www.ncbi.nlm.nih.gov/pubmed/21202610
http://dx.doi.org/10.1107/S1600536808014190
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author Nirmala, S.
Kamala, E. Theboral Sugi
Sudha, L.
Arumugam, N.
Raghunathan, R.
author_facet Nirmala, S.
Kamala, E. Theboral Sugi
Sudha, L.
Arumugam, N.
Raghunathan, R.
author_sort Nirmala, S.
collection PubMed
description In the title compound, C(37)H(33)BrN(4)O(6), the pyrrolidine ring adopts an envelope conformation. The β-lactam ring is planar and makes dihedral angles of 70.16 (13) and 28.32 (13)° with the phenyl and 4-methoxy­phenyl rings, respectively. The mol­ecular packing is stabilized by intra­molecular C—H⋯O inter­actions and the crystal packing is determined by inter­molecular N—H⋯O hydrogen bonds, and C—H⋯O and C—H⋯π inter­actions.
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spelling pubmed-29613542010-12-30 Methyl 3-(4-bromo­phen­yl)-2-(1H-indol-3-ylmeth­yl)-5-[1-(4-methoxy­phen­yl)-4-oxo-2-phenyl­azetidin-2-yl]-4-nitro­pyrrolidine-2-carboxyl­ate Nirmala, S. Kamala, E. Theboral Sugi Sudha, L. Arumugam, N. Raghunathan, R. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(37)H(33)BrN(4)O(6), the pyrrolidine ring adopts an envelope conformation. The β-lactam ring is planar and makes dihedral angles of 70.16 (13) and 28.32 (13)° with the phenyl and 4-methoxy­phenyl rings, respectively. The mol­ecular packing is stabilized by intra­molecular C—H⋯O inter­actions and the crystal packing is determined by inter­molecular N—H⋯O hydrogen bonds, and C—H⋯O and C—H⋯π inter­actions. International Union of Crystallography 2008-05-17 /pmc/articles/PMC2961354/ /pubmed/21202610 http://dx.doi.org/10.1107/S1600536808014190 Text en © Nirmala et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Nirmala, S.
Kamala, E. Theboral Sugi
Sudha, L.
Arumugam, N.
Raghunathan, R.
Methyl 3-(4-bromo­phen­yl)-2-(1H-indol-3-ylmeth­yl)-5-[1-(4-methoxy­phen­yl)-4-oxo-2-phenyl­azetidin-2-yl]-4-nitro­pyrrolidine-2-carboxyl­ate
title Methyl 3-(4-bromo­phen­yl)-2-(1H-indol-3-ylmeth­yl)-5-[1-(4-methoxy­phen­yl)-4-oxo-2-phenyl­azetidin-2-yl]-4-nitro­pyrrolidine-2-carboxyl­ate
title_full Methyl 3-(4-bromo­phen­yl)-2-(1H-indol-3-ylmeth­yl)-5-[1-(4-methoxy­phen­yl)-4-oxo-2-phenyl­azetidin-2-yl]-4-nitro­pyrrolidine-2-carboxyl­ate
title_fullStr Methyl 3-(4-bromo­phen­yl)-2-(1H-indol-3-ylmeth­yl)-5-[1-(4-methoxy­phen­yl)-4-oxo-2-phenyl­azetidin-2-yl]-4-nitro­pyrrolidine-2-carboxyl­ate
title_full_unstemmed Methyl 3-(4-bromo­phen­yl)-2-(1H-indol-3-ylmeth­yl)-5-[1-(4-methoxy­phen­yl)-4-oxo-2-phenyl­azetidin-2-yl]-4-nitro­pyrrolidine-2-carboxyl­ate
title_short Methyl 3-(4-bromo­phen­yl)-2-(1H-indol-3-ylmeth­yl)-5-[1-(4-methoxy­phen­yl)-4-oxo-2-phenyl­azetidin-2-yl]-4-nitro­pyrrolidine-2-carboxyl­ate
title_sort methyl 3-(4-bromo­phen­yl)-2-(1h-indol-3-ylmeth­yl)-5-[1-(4-methoxy­phen­yl)-4-oxo-2-phenyl­azetidin-2-yl]-4-nitro­pyrrolidine-2-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961354/
https://www.ncbi.nlm.nih.gov/pubmed/21202610
http://dx.doi.org/10.1107/S1600536808014190
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AT sudhal methyl34bromophenyl21hindol3ylmethyl514methoxyphenyl4oxo2phenylazetidin2yl4nitropyrrolidine2carboxylate
AT arumugamn methyl34bromophenyl21hindol3ylmethyl514methoxyphenyl4oxo2phenylazetidin2yl4nitropyrrolidine2carboxylate
AT raghunathanr methyl34bromophenyl21hindol3ylmethyl514methoxyphenyl4oxo2phenylazetidin2yl4nitropyrrolidine2carboxylate

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