Mesaconitine

The title compound, (1α,3α,6α,14α,15α,16β)-3,8,13,14,15-penta­hydr­oxy-1,6,16-trimeth­oxy-4-methoxy­methyl-20-methyl­acon­itan-8,14-diyl 8-acetate 14-benzoate, C(33)H(45)NO(11), a C(19) diterpenoid alkaloid, obtained from the roots of Aconitum kusnezoffii, has been crystallographically characterized...

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Detalles Bibliográficos
Autores principales: He, Dao-Hang, Zhu, Yong-Chuang, Hu, Ai-Xi
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961389/
https://www.ncbi.nlm.nih.gov/pubmed/21202557
http://dx.doi.org/10.1107/S1600536808013147
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author He, Dao-Hang
Zhu, Yong-Chuang
Hu, Ai-Xi
author_facet He, Dao-Hang
Zhu, Yong-Chuang
Hu, Ai-Xi
author_sort He, Dao-Hang
collection PubMed
description The title compound, (1α,3α,6α,14α,15α,16β)-3,8,13,14,15-penta­hydr­oxy-1,6,16-trimeth­oxy-4-methoxy­methyl-20-methyl­acon­itan-8,14-diyl 8-acetate 14-benzoate, C(33)H(45)NO(11), a C(19) diterpenoid alkaloid, obtained from the roots of Aconitum kusnezoffii, has been crystallographically characterized in this study. Rings A, B and E have chair conformations, rings C and F display envelope conformations, and ring D adopts a boat conformation. There are inter- and intra­molecular O—H⋯O hydrogen bonds, the latter resulting in the formation of a non-planar seven-membered ring. The inter­molecular inter­actions link the mol­ecules into a two-dimensional network.
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spelling pubmed-29613892010-12-30 Mesaconitine He, Dao-Hang Zhu, Yong-Chuang Hu, Ai-Xi Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, (1α,3α,6α,14α,15α,16β)-3,8,13,14,15-penta­hydr­oxy-1,6,16-trimeth­oxy-4-methoxy­methyl-20-methyl­acon­itan-8,14-diyl 8-acetate 14-benzoate, C(33)H(45)NO(11), a C(19) diterpenoid alkaloid, obtained from the roots of Aconitum kusnezoffii, has been crystallographically characterized in this study. Rings A, B and E have chair conformations, rings C and F display envelope conformations, and ring D adopts a boat conformation. There are inter- and intra­molecular O—H⋯O hydrogen bonds, the latter resulting in the formation of a non-planar seven-membered ring. The inter­molecular inter­actions link the mol­ecules into a two-dimensional network. International Union of Crystallography 2008-05-10 /pmc/articles/PMC2961389/ /pubmed/21202557 http://dx.doi.org/10.1107/S1600536808013147 Text en © He et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
He, Dao-Hang
Zhu, Yong-Chuang
Hu, Ai-Xi
Mesaconitine
title Mesaconitine
title_full Mesaconitine
title_fullStr Mesaconitine
title_full_unstemmed Mesaconitine
title_short Mesaconitine
title_sort mesaconitine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961389/
https://www.ncbi.nlm.nih.gov/pubmed/21202557
http://dx.doi.org/10.1107/S1600536808013147
work_keys_str_mv AT hedaohang mesaconitine
AT zhuyongchuang mesaconitine
AT huaixi mesaconitine

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