(2S,3R)-2-[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl­amino]-3-hydroxy­butyric acid monohydrate

In the title compound, C(11)H(17)N(3)O(6)·H(2)O, an important building block of the medicine cefbuperazone sodium, the piperazine ring adopts a screw-boat conformation. Inter­molecular O—H⋯O and intra­molecular N—H⋯O hydrogen bonds are observed. The water mol­ecule participates as both donor and acc...

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Detalles Bibliográficos
Autores principales: Ji, Chun-xiang, Cui, Yong-tao, Yang, Dong-ling, Guo, Cheng
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961655/
https://www.ncbi.nlm.nih.gov/pubmed/21202922
http://dx.doi.org/10.1107/S1600536808017832
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author Ji, Chun-xiang
Cui, Yong-tao
Yang, Dong-ling
Guo, Cheng
author_facet Ji, Chun-xiang
Cui, Yong-tao
Yang, Dong-ling
Guo, Cheng
author_sort Ji, Chun-xiang
collection PubMed
description In the title compound, C(11)H(17)N(3)O(6)·H(2)O, an important building block of the medicine cefbuperazone sodium, the piperazine ring adopts a screw-boat conformation. Inter­molecular O—H⋯O and intra­molecular N—H⋯O hydrogen bonds are observed. The water mol­ecule participates as both donor and acceptor in this framework.
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spelling pubmed-29616552010-12-30 (2S,3R)-2-[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl­amino]-3-hydroxy­butyric acid monohydrate Ji, Chun-xiang Cui, Yong-tao Yang, Dong-ling Guo, Cheng Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(11)H(17)N(3)O(6)·H(2)O, an important building block of the medicine cefbuperazone sodium, the piperazine ring adopts a screw-boat conformation. Inter­molecular O—H⋯O and intra­molecular N—H⋯O hydrogen bonds are observed. The water mol­ecule participates as both donor and acceptor in this framework. International Union of Crystallography 2008-06-19 /pmc/articles/PMC2961655/ /pubmed/21202922 http://dx.doi.org/10.1107/S1600536808017832 Text en © Ji et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Ji, Chun-xiang
Cui, Yong-tao
Yang, Dong-ling
Guo, Cheng
(2S,3R)-2-[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl­amino]-3-hydroxy­butyric acid monohydrate
title (2S,3R)-2-[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl­amino]-3-hydroxy­butyric acid monohydrate
title_full (2S,3R)-2-[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl­amino]-3-hydroxy­butyric acid monohydrate
title_fullStr (2S,3R)-2-[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl­amino]-3-hydroxy­butyric acid monohydrate
title_full_unstemmed (2S,3R)-2-[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl­amino]-3-hydroxy­butyric acid monohydrate
title_short (2S,3R)-2-[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl­amino]-3-hydroxy­butyric acid monohydrate
title_sort (2s,3r)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl­amino]-3-hydroxy­butyric acid monohydrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961655/
https://www.ncbi.nlm.nih.gov/pubmed/21202922
http://dx.doi.org/10.1107/S1600536808017832
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