3-[5-(4-Fluoro­phen­yl)-1,3,4-thia­diazol-2-yl]-2-(4-methoxy­phen­yl)-1,3-thia­zolidin-4-one

The title compound, C(18)H(14)FN(3)O(2)S(2), was synthesized by the reaction of 5-(4-fluoro­phen­yl)-N-(4-methoxy­benzyl­idene)-1,3,4-thia­diazol-2-amine and mercaptoacetic acid. The thia­zolidinone ring adopts a twist conformation. The 4-methoxy­phenyl ring is almost perpendicular to the thia­diazo...

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Detalles Bibliográficos
Autores principales: Yin, Li-He, Wan, Rong, Han, Feng, Wang, Bin, Wang, Jin-Tang
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961680/
https://www.ncbi.nlm.nih.gov/pubmed/21202977
http://dx.doi.org/10.1107/S1600536808019089
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author Yin, Li-He
Wan, Rong
Han, Feng
Wang, Bin
Wang, Jin-Tang
author_facet Yin, Li-He
Wan, Rong
Han, Feng
Wang, Bin
Wang, Jin-Tang
author_sort Yin, Li-He
collection PubMed
description The title compound, C(18)H(14)FN(3)O(2)S(2), was synthesized by the reaction of 5-(4-fluoro­phen­yl)-N-(4-methoxy­benzyl­idene)-1,3,4-thia­diazol-2-amine and mercaptoacetic acid. The thia­zolidinone ring adopts a twist conformation. The 4-methoxy­phenyl ring is almost perpendicular to the thia­diazole ring, making a dihedral angle of 88.4 (3)°. The 4-fluoro­phenyl ring is nearly coplanar with the thia­diazole ring, the dihedral angle being 6.8 (3)°. The crystal structure involves C—H⋯N, C—H⋯O and C—H⋯S hydrogen bonds.
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spelling pubmed-29616802010-12-30 3-[5-(4-Fluoro­phen­yl)-1,3,4-thia­diazol-2-yl]-2-(4-methoxy­phen­yl)-1,3-thia­zolidin-4-one Yin, Li-He Wan, Rong Han, Feng Wang, Bin Wang, Jin-Tang Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(18)H(14)FN(3)O(2)S(2), was synthesized by the reaction of 5-(4-fluoro­phen­yl)-N-(4-methoxy­benzyl­idene)-1,3,4-thia­diazol-2-amine and mercaptoacetic acid. The thia­zolidinone ring adopts a twist conformation. The 4-methoxy­phenyl ring is almost perpendicular to the thia­diazole ring, making a dihedral angle of 88.4 (3)°. The 4-fluoro­phenyl ring is nearly coplanar with the thia­diazole ring, the dihedral angle being 6.8 (3)°. The crystal structure involves C—H⋯N, C—H⋯O and C—H⋯S hydrogen bonds. International Union of Crystallography 2008-06-28 /pmc/articles/PMC2961680/ /pubmed/21202977 http://dx.doi.org/10.1107/S1600536808019089 Text en © Yin et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Yin, Li-He
Wan, Rong
Han, Feng
Wang, Bin
Wang, Jin-Tang
3-[5-(4-Fluoro­phen­yl)-1,3,4-thia­diazol-2-yl]-2-(4-methoxy­phen­yl)-1,3-thia­zolidin-4-one
title 3-[5-(4-Fluoro­phen­yl)-1,3,4-thia­diazol-2-yl]-2-(4-methoxy­phen­yl)-1,3-thia­zolidin-4-one
title_full 3-[5-(4-Fluoro­phen­yl)-1,3,4-thia­diazol-2-yl]-2-(4-methoxy­phen­yl)-1,3-thia­zolidin-4-one
title_fullStr 3-[5-(4-Fluoro­phen­yl)-1,3,4-thia­diazol-2-yl]-2-(4-methoxy­phen­yl)-1,3-thia­zolidin-4-one
title_full_unstemmed 3-[5-(4-Fluoro­phen­yl)-1,3,4-thia­diazol-2-yl]-2-(4-methoxy­phen­yl)-1,3-thia­zolidin-4-one
title_short 3-[5-(4-Fluoro­phen­yl)-1,3,4-thia­diazol-2-yl]-2-(4-methoxy­phen­yl)-1,3-thia­zolidin-4-one
title_sort 3-[5-(4-fluoro­phen­yl)-1,3,4-thia­diazol-2-yl]-2-(4-methoxy­phen­yl)-1,3-thia­zolidin-4-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961680/
https://www.ncbi.nlm.nih.gov/pubmed/21202977
http://dx.doi.org/10.1107/S1600536808019089
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AT wangjintang 354fluorophenyl134thiadiazol2yl24methoxyphenyl13thiazolidin4one

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