4-Chloro-3-fluoro-2-methyl­aniline–pyrrolidine-2,5-dione (1/1)

Chlorination of 3-fluoro-2-methyl­aniline with N-chloro­succinimide gave one major regioisomer whose structure was determined by X-ray crystallography. The product was found to have cocrystallized with succinimide, giving the title compound, C(7)H(7)ClFN·C(4)H(5)NO(2). The crystal structure is stabi...

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Detalles Bibliográficos
Autores principales: Mayes, Benjamin A., McGarry, Patrick, Moussa, Adel, Watkin, David J.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961731/
https://www.ncbi.nlm.nih.gov/pubmed/21202974
http://dx.doi.org/10.1107/S1600536808018795
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author Mayes, Benjamin A.
McGarry, Patrick
Moussa, Adel
Watkin, David J.
author_facet Mayes, Benjamin A.
McGarry, Patrick
Moussa, Adel
Watkin, David J.
author_sort Mayes, Benjamin A.
collection PubMed
description Chlorination of 3-fluoro-2-methyl­aniline with N-chloro­succinimide gave one major regioisomer whose structure was determined by X-ray crystallography. The product was found to have cocrystallized with succinimide, giving the title compound, C(7)H(7)ClFN·C(4)H(5)NO(2). The crystal structure is stabilized by N—H⋯O hydrogen-bonding and π–π stacking inter­actions with a centroid–centroid distance of 3.4501 (8) Å.
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spelling pubmed-29617312010-12-30 4-Chloro-3-fluoro-2-methyl­aniline–pyrrolidine-2,5-dione (1/1) Mayes, Benjamin A. McGarry, Patrick Moussa, Adel Watkin, David J. Acta Crystallogr Sect E Struct Rep Online Organic Papers Chlorination of 3-fluoro-2-methyl­aniline with N-chloro­succinimide gave one major regioisomer whose structure was determined by X-ray crystallography. The product was found to have cocrystallized with succinimide, giving the title compound, C(7)H(7)ClFN·C(4)H(5)NO(2). The crystal structure is stabilized by N—H⋯O hydrogen-bonding and π–π stacking inter­actions with a centroid–centroid distance of 3.4501 (8) Å. International Union of Crystallography 2008-06-28 /pmc/articles/PMC2961731/ /pubmed/21202974 http://dx.doi.org/10.1107/S1600536808018795 Text en © Mayes et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Mayes, Benjamin A.
McGarry, Patrick
Moussa, Adel
Watkin, David J.
4-Chloro-3-fluoro-2-methyl­aniline–pyrrolidine-2,5-dione (1/1)
title 4-Chloro-3-fluoro-2-methyl­aniline–pyrrolidine-2,5-dione (1/1)
title_full 4-Chloro-3-fluoro-2-methyl­aniline–pyrrolidine-2,5-dione (1/1)
title_fullStr 4-Chloro-3-fluoro-2-methyl­aniline–pyrrolidine-2,5-dione (1/1)
title_full_unstemmed 4-Chloro-3-fluoro-2-methyl­aniline–pyrrolidine-2,5-dione (1/1)
title_short 4-Chloro-3-fluoro-2-methyl­aniline–pyrrolidine-2,5-dione (1/1)
title_sort 4-chloro-3-fluoro-2-methyl­aniline–pyrrolidine-2,5-dione (1/1)
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961731/
https://www.ncbi.nlm.nih.gov/pubmed/21202974
http://dx.doi.org/10.1107/S1600536808018795
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AT moussaadel 4chloro3fluoro2methylanilinepyrrolidine25dione11
AT watkindavidj 4chloro3fluoro2methylanilinepyrrolidine25dione11

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