Cargando…

t-3-Benzyl-r-2,c-6-bis­(4-methoxy­phen­yl)piperidin-4-one oxime

In the title mol­ecule, C(26)H(28)N(2)O(3), the piperidine ring adopts a chair conformation. The two methoxy­phenyl groups attached to the piperidine ring at positions 2 and 6 have equatorial orientations, and make a dihedral angle of 80.72 (15)°. The benzyl group at position 3 has an equatorial ori...

Descripción completa

Detalles Bibliográficos
Autores principales: Jayabharathi, J., Thangamani, A., Balamurugan, S., Thiruvalluvar, A., Linden, A.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961741/
https://www.ncbi.nlm.nih.gov/pubmed/21202850
http://dx.doi.org/10.1107/S1600536808016449
_version_ 1782189055031640064
author Jayabharathi, J.
Thangamani, A.
Balamurugan, S.
Thiruvalluvar, A.
Linden, A.
author_facet Jayabharathi, J.
Thangamani, A.
Balamurugan, S.
Thiruvalluvar, A.
Linden, A.
author_sort Jayabharathi, J.
collection PubMed
description In the title mol­ecule, C(26)H(28)N(2)O(3), the piperidine ring adopts a chair conformation. The two methoxy­phenyl groups attached to the piperidine ring at positions 2 and 6 have equatorial orientations, and make a dihedral angle of 80.72 (15)°. The benzyl group at position 3 has an equatorial orientation. The oxime group at position 4 has a bi­sectional orientation. The ring of the benzyl group makes dihedral angles of 64.71 (16) and 84.79 (17)° with the two benzene rings. Mol­ecules are linked by inter­molecular N—H⋯O, O—H⋯N and C—H⋯O hydrogen bonds, and C—H⋯π inter­actions. There is also a C—H⋯O intra­molecular inter­action.
format Text
id pubmed-2961741
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29617412010-12-30 t-3-Benzyl-r-2,c-6-bis­(4-methoxy­phen­yl)piperidin-4-one oxime Jayabharathi, J. Thangamani, A. Balamurugan, S. Thiruvalluvar, A. Linden, A. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title mol­ecule, C(26)H(28)N(2)O(3), the piperidine ring adopts a chair conformation. The two methoxy­phenyl groups attached to the piperidine ring at positions 2 and 6 have equatorial orientations, and make a dihedral angle of 80.72 (15)°. The benzyl group at position 3 has an equatorial orientation. The oxime group at position 4 has a bi­sectional orientation. The ring of the benzyl group makes dihedral angles of 64.71 (16) and 84.79 (17)° with the two benzene rings. Mol­ecules are linked by inter­molecular N—H⋯O, O—H⋯N and C—H⋯O hydrogen bonds, and C—H⋯π inter­actions. There is also a C—H⋯O intra­molecular inter­action. International Union of Crystallography 2008-06-07 /pmc/articles/PMC2961741/ /pubmed/21202850 http://dx.doi.org/10.1107/S1600536808016449 Text en © Jayabharathi et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Jayabharathi, J.
Thangamani, A.
Balamurugan, S.
Thiruvalluvar, A.
Linden, A.
t-3-Benzyl-r-2,c-6-bis­(4-methoxy­phen­yl)piperidin-4-one oxime
title t-3-Benzyl-r-2,c-6-bis­(4-methoxy­phen­yl)piperidin-4-one oxime
title_full t-3-Benzyl-r-2,c-6-bis­(4-methoxy­phen­yl)piperidin-4-one oxime
title_fullStr t-3-Benzyl-r-2,c-6-bis­(4-methoxy­phen­yl)piperidin-4-one oxime
title_full_unstemmed t-3-Benzyl-r-2,c-6-bis­(4-methoxy­phen­yl)piperidin-4-one oxime
title_short t-3-Benzyl-r-2,c-6-bis­(4-methoxy­phen­yl)piperidin-4-one oxime
title_sort t-3-benzyl-r-2,c-6-bis­(4-methoxy­phen­yl)piperidin-4-one oxime
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961741/
https://www.ncbi.nlm.nih.gov/pubmed/21202850
http://dx.doi.org/10.1107/S1600536808016449
work_keys_str_mv AT jayabharathij t3benzylr2c6bis4methoxyphenylpiperidin4oneoxime
AT thangamania t3benzylr2c6bis4methoxyphenylpiperidin4oneoxime
AT balamurugans t3benzylr2c6bis4methoxyphenylpiperidin4oneoxime
AT thiruvalluvara t3benzylr2c6bis4methoxyphenylpiperidin4oneoxime
AT lindena t3benzylr2c6bis4methoxyphenylpiperidin4oneoxime