1-Hydroxy­ethyl-2-methyl-5-nitro­imidazolium 3-carb­oxy-4-hydroxy­benzene­sulfonate

Cocrystallization of 1-hydroxy­ethyl-2-methyl-5-nitroimidazole (metronidazole) and 5-sulfosalicylic acid (5-H(2)SSA) from methanol solution yields the title salt, C(6)H(10)N(3)O(3) (+)·C(7)H(5)O(6)S(−). In the crystal structure, the ions are linked by a combination of inter­molecular O—H⋯O, N—H⋯O an...

Descripción completa

Detalles Bibliográficos
Autor principal: Yang, Bo
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961761/
https://www.ncbi.nlm.nih.gov/pubmed/21202961
http://dx.doi.org/10.1107/S1600536808018643
_version_ 1782189059765960704
author Yang, Bo
author_facet Yang, Bo
author_sort Yang, Bo
collection PubMed
description Cocrystallization of 1-hydroxy­ethyl-2-methyl-5-nitroimidazole (metronidazole) and 5-sulfosalicylic acid (5-H(2)SSA) from methanol solution yields the title salt, C(6)H(10)N(3)O(3) (+)·C(7)H(5)O(6)S(−). In the crystal structure, the ions are linked by a combination of inter­molecular O—H⋯O, N—H⋯O and C—H⋯O hydrogen bonds, forming a three-dimensional framework. The hydroxyl group of the cation is disordered over two sites in a 0.860 (4):0.140 (4) ratio.
format Text
id pubmed-2961761
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29617612010-12-30 1-Hydroxy­ethyl-2-methyl-5-nitro­imidazolium 3-carb­oxy-4-hydroxy­benzene­sulfonate Yang, Bo Acta Crystallogr Sect E Struct Rep Online Organic Papers Cocrystallization of 1-hydroxy­ethyl-2-methyl-5-nitroimidazole (metronidazole) and 5-sulfosalicylic acid (5-H(2)SSA) from methanol solution yields the title salt, C(6)H(10)N(3)O(3) (+)·C(7)H(5)O(6)S(−). In the crystal structure, the ions are linked by a combination of inter­molecular O—H⋯O, N—H⋯O and C—H⋯O hydrogen bonds, forming a three-dimensional framework. The hydroxyl group of the cation is disordered over two sites in a 0.860 (4):0.140 (4) ratio. International Union of Crystallography 2008-06-25 /pmc/articles/PMC2961761/ /pubmed/21202961 http://dx.doi.org/10.1107/S1600536808018643 Text en © Bo Yang 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Yang, Bo
1-Hydroxy­ethyl-2-methyl-5-nitro­imidazolium 3-carb­oxy-4-hydroxy­benzene­sulfonate
title 1-Hydroxy­ethyl-2-methyl-5-nitro­imidazolium 3-carb­oxy-4-hydroxy­benzene­sulfonate
title_full 1-Hydroxy­ethyl-2-methyl-5-nitro­imidazolium 3-carb­oxy-4-hydroxy­benzene­sulfonate
title_fullStr 1-Hydroxy­ethyl-2-methyl-5-nitro­imidazolium 3-carb­oxy-4-hydroxy­benzene­sulfonate
title_full_unstemmed 1-Hydroxy­ethyl-2-methyl-5-nitro­imidazolium 3-carb­oxy-4-hydroxy­benzene­sulfonate
title_short 1-Hydroxy­ethyl-2-methyl-5-nitro­imidazolium 3-carb­oxy-4-hydroxy­benzene­sulfonate
title_sort 1-hydroxy­ethyl-2-methyl-5-nitro­imidazolium 3-carb­oxy-4-hydroxy­benzene­sulfonate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961761/
https://www.ncbi.nlm.nih.gov/pubmed/21202961
http://dx.doi.org/10.1107/S1600536808018643
work_keys_str_mv AT yangbo 1hydroxyethyl2methyl5nitroimidazolium3carboxy4hydroxybenzenesulfonate

Ejemplares similares