2-(Tricyclo[3.3.1.1(3,7)]dec-2-ylamino)ethanol hemihydrate

The title adamantane derivative, C(12)H(21)NO·0.5H(2)O, was synthesized as part of an investigation into the biological activities of cage amino–alcohol compounds as potential anti-tuberculosis agents. The structure displays inter­molecular O—H⋯N, N—H⋯O, O—H⋯O hydrogen bonding and a layered packing...

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Detalles Bibliográficos
Autores principales: Boyle, Grant A., Govender, Thavendran, Kruger, Hendrik G., Onajole, Oluseye K.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961807/
https://www.ncbi.nlm.nih.gov/pubmed/21202865
http://dx.doi.org/10.1107/S1600536808016851
Descripción
Sumario:The title adamantane derivative, C(12)H(21)NO·0.5H(2)O, was synthesized as part of an investigation into the biological activities of cage amino–alcohol compounds as potential anti-tuberculosis agents. The structure displays inter­molecular O—H⋯N, N—H⋯O, O—H⋯O hydrogen bonding and a layered packing structure with distinct hydro­philic and hydro­phobic regions. The water molecule lies on a twofold rotation axis.

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