2-(Tricyclo[3.3.1.1(3,7)]dec-2-ylamino)ethanol hemihydrate

The title adamantane derivative, C(12)H(21)NO·0.5H(2)O, was synthesized as part of an investigation into the biological activities of cage amino–alcohol compounds as potential anti-tuberculosis agents. The structure displays inter­molecular O—H⋯N, N—H⋯O, O—H⋯O hydrogen bonding and a layered packing...

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Detalles Bibliográficos
Autores principales: Boyle, Grant A., Govender, Thavendran, Kruger, Hendrik G., Onajole, Oluseye K.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961807/
https://www.ncbi.nlm.nih.gov/pubmed/21202865
http://dx.doi.org/10.1107/S1600536808016851
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author Boyle, Grant A.
Govender, Thavendran
Kruger, Hendrik G.
Onajole, Oluseye K.
author_facet Boyle, Grant A.
Govender, Thavendran
Kruger, Hendrik G.
Onajole, Oluseye K.
author_sort Boyle, Grant A.
collection PubMed
description The title adamantane derivative, C(12)H(21)NO·0.5H(2)O, was synthesized as part of an investigation into the biological activities of cage amino–alcohol compounds as potential anti-tuberculosis agents. The structure displays inter­molecular O—H⋯N, N—H⋯O, O—H⋯O hydrogen bonding and a layered packing structure with distinct hydro­philic and hydro­phobic regions. The water molecule lies on a twofold rotation axis.
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spelling pubmed-29618072010-12-30 2-(Tricyclo[3.3.1.1(3,7)]dec-2-ylamino)ethanol hemihydrate Boyle, Grant A. Govender, Thavendran Kruger, Hendrik G. Onajole, Oluseye K. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title adamantane derivative, C(12)H(21)NO·0.5H(2)O, was synthesized as part of an investigation into the biological activities of cage amino–alcohol compounds as potential anti-tuberculosis agents. The structure displays inter­molecular O—H⋯N, N—H⋯O, O—H⋯O hydrogen bonding and a layered packing structure with distinct hydro­philic and hydro­phobic regions. The water molecule lies on a twofold rotation axis. International Union of Crystallography 2008-06-07 /pmc/articles/PMC2961807/ /pubmed/21202865 http://dx.doi.org/10.1107/S1600536808016851 Text en © Boyle et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Boyle, Grant A.
Govender, Thavendran
Kruger, Hendrik G.
Onajole, Oluseye K.
2-(Tricyclo[3.3.1.1(3,7)]dec-2-ylamino)ethanol hemihydrate
title 2-(Tricyclo[3.3.1.1(3,7)]dec-2-ylamino)ethanol hemihydrate
title_full 2-(Tricyclo[3.3.1.1(3,7)]dec-2-ylamino)ethanol hemihydrate
title_fullStr 2-(Tricyclo[3.3.1.1(3,7)]dec-2-ylamino)ethanol hemihydrate
title_full_unstemmed 2-(Tricyclo[3.3.1.1(3,7)]dec-2-ylamino)ethanol hemihydrate
title_short 2-(Tricyclo[3.3.1.1(3,7)]dec-2-ylamino)ethanol hemihydrate
title_sort 2-(tricyclo[3.3.1.1(3,7)]dec-2-ylamino)ethanol hemihydrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961807/
https://www.ncbi.nlm.nih.gov/pubmed/21202865
http://dx.doi.org/10.1107/S1600536808016851
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AT onajoleoluseyek 2tricyclo331137dec2ylaminoethanolhemihydrate

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