4-(7-Acet­oxy-6-meth­oxy-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate

The title compound, C(21)H(18)O(7), is an important inter­mediate in the synthesis of 3-(4-hydroxy­phen­yl)-4-methyl-6-meth­oxy-7-hydroxy­coumarin, which is a nonsteroidal analogue of 2-methoxy­estradiol (2-ME). The substituent benzene ring is not in the same plane as the coumarin ring system, with...

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Detalles Bibliográficos
Autores principales: Jiang, Hao, Xia, Peng, Zhang, Qian
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961866/
https://www.ncbi.nlm.nih.gov/pubmed/21202867
http://dx.doi.org/10.1107/S1600536808012890
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author Jiang, Hao
Xia, Peng
Zhang, Qian
author_facet Jiang, Hao
Xia, Peng
Zhang, Qian
author_sort Jiang, Hao
collection PubMed
description The title compound, C(21)H(18)O(7), is an important inter­mediate in the synthesis of 3-(4-hydroxy­phen­yl)-4-methyl-6-meth­oxy-7-hydroxy­coumarin, which is a nonsteroidal analogue of 2-methoxy­estradiol (2-ME). The substituent benzene ring is not in the same plane as the coumarin ring system, with a dihedral angle of 66.88 (10)°. There are some weak inter­molecular C—H⋯O inter­actions. One carbonyl O atom is disordered over two sites, with occupancies of 0.6 and 0.4.
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spelling pubmed-29618662010-12-30 4-(7-Acet­oxy-6-meth­oxy-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate Jiang, Hao Xia, Peng Zhang, Qian Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(21)H(18)O(7), is an important inter­mediate in the synthesis of 3-(4-hydroxy­phen­yl)-4-methyl-6-meth­oxy-7-hydroxy­coumarin, which is a nonsteroidal analogue of 2-methoxy­estradiol (2-ME). The substituent benzene ring is not in the same plane as the coumarin ring system, with a dihedral angle of 66.88 (10)°. There are some weak inter­molecular C—H⋯O inter­actions. One carbonyl O atom is disordered over two sites, with occupancies of 0.6 and 0.4. International Union of Crystallography 2008-06-07 /pmc/articles/PMC2961866/ /pubmed/21202867 http://dx.doi.org/10.1107/S1600536808012890 Text en © Jiang et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Jiang, Hao
Xia, Peng
Zhang, Qian
4-(7-Acet­oxy-6-meth­oxy-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate
title 4-(7-Acet­oxy-6-meth­oxy-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate
title_full 4-(7-Acet­oxy-6-meth­oxy-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate
title_fullStr 4-(7-Acet­oxy-6-meth­oxy-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate
title_full_unstemmed 4-(7-Acet­oxy-6-meth­oxy-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate
title_short 4-(7-Acet­oxy-6-meth­oxy-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate
title_sort 4-(7-acet­oxy-6-meth­oxy-4-methyl-2-oxo-2h-chromen-3-yl)phenyl acetate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961866/
https://www.ncbi.nlm.nih.gov/pubmed/21202867
http://dx.doi.org/10.1107/S1600536808012890
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AT xiapeng 47acetoxy6methoxy4methyl2oxo2hchromen3ylphenylacetate
AT zhangqian 47acetoxy6methoxy4methyl2oxo2hchromen3ylphenylacetate

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