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Degradation of atorvastatin: (1R,2S,4S,5S)-4-(4-fluorophenyl)-2-hydroperoxy-4-hydroxy-2-isopropyl-N,5-diphenyl-3,6-dioxabicyclo[3.1.0]hexane-1-carboxamide
The degradation of atorvastatin calcium in methanol and hydrogen peroxide results in the crystallization of the title compound, C(26)H(24)FNO(6), which shows several differences compared with the starting compound. In the crystal structure of the title compound, intra- and intermolecular hydrogen b...
Autores principales: | Ashfaq, Muhammad, Tahir, Muhammad Nawaz, Khan, Islam Ullah, Iqbal, Mohammad S., Arshad, Muhammad Nadeem |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962052/ https://www.ncbi.nlm.nih.gov/pubmed/21203252 http://dx.doi.org/10.1107/S1600536808022265 |
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