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2-Methoxyphenyl 2-{2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetamido}acetate
The title compound, amtolmetin guacil, C(24)H(24)N(2)O(5), is a new gastroprotective non-steroidal anti-inflammatory drug. In the crystal structure, the drug molecule is linked into a one-dimensional structure along the c axis by weak N—H⋯O interactions between the amide groups. C—H⋯O and C—H⋯π in...
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Formato: | Texto |
Lenguaje: | English |
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International Union of Crystallography
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962070/ https://www.ncbi.nlm.nih.gov/pubmed/21203154 http://dx.doi.org/10.1107/S1600536808020722 |
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author | Lou, Ben-Yong Guo, Xia Lin, Qi |
author_facet | Lou, Ben-Yong Guo, Xia Lin, Qi |
author_sort | Lou, Ben-Yong |
collection | PubMed |
description | The title compound, amtolmetin guacil, C(24)H(24)N(2)O(5), is a new gastroprotective non-steroidal anti-inflammatory drug. In the crystal structure, the drug molecule is linked into a one-dimensional structure along the c axis by weak N—H⋯O interactions between the amide groups. C—H⋯O and C—H⋯π interactions influence the packing. |
format | Text |
id | pubmed-2962070 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29620702010-12-30 2-Methoxyphenyl 2-{2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetamido}acetate Lou, Ben-Yong Guo, Xia Lin, Qi Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, amtolmetin guacil, C(24)H(24)N(2)O(5), is a new gastroprotective non-steroidal anti-inflammatory drug. In the crystal structure, the drug molecule is linked into a one-dimensional structure along the c axis by weak N—H⋯O interactions between the amide groups. C—H⋯O and C—H⋯π interactions influence the packing. International Union of Crystallography 2008-07-09 /pmc/articles/PMC2962070/ /pubmed/21203154 http://dx.doi.org/10.1107/S1600536808020722 Text en © Lou et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Lou, Ben-Yong Guo, Xia Lin, Qi 2-Methoxyphenyl 2-{2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetamido}acetate |
title | 2-Methoxyphenyl 2-{2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetamido}acetate |
title_full | 2-Methoxyphenyl 2-{2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetamido}acetate |
title_fullStr | 2-Methoxyphenyl 2-{2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetamido}acetate |
title_full_unstemmed | 2-Methoxyphenyl 2-{2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetamido}acetate |
title_short | 2-Methoxyphenyl 2-{2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetamido}acetate |
title_sort | 2-methoxyphenyl 2-{2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetamido}acetate |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962070/ https://www.ncbi.nlm.nih.gov/pubmed/21203154 http://dx.doi.org/10.1107/S1600536808020722 |
work_keys_str_mv | AT loubenyong 2methoxyphenyl221methyl54methylbenzoylpyrrol2ylacetamidoacetate AT guoxia 2methoxyphenyl221methyl54methylbenzoylpyrrol2ylacetamidoacetate AT linqi 2methoxyphenyl221methyl54methylbenzoylpyrrol2ylacetamidoacetate |