2-Methoxy­phenyl 2-{2-[1-methyl-5-(4-methyl­benzo­yl)pyrrol-2-yl]acetamido}acetate

The title compound, amtolmetin guacil, C(24)H(24)N(2)O(5), is a new gastroprotective non-steroidal anti-inflammatory drug. In the crystal structure, the drug mol­ecule is linked into a one-dimensional structure along the c axis by weak N—H⋯O inter­actions between the amide groups. C—H⋯O and C—H⋯π in...

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Detalles Bibliográficos
Autores principales: Lou, Ben-Yong, Guo, Xia, Lin, Qi
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962070/
https://www.ncbi.nlm.nih.gov/pubmed/21203154
http://dx.doi.org/10.1107/S1600536808020722
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author Lou, Ben-Yong
Guo, Xia
Lin, Qi
author_facet Lou, Ben-Yong
Guo, Xia
Lin, Qi
author_sort Lou, Ben-Yong
collection PubMed
description The title compound, amtolmetin guacil, C(24)H(24)N(2)O(5), is a new gastroprotective non-steroidal anti-inflammatory drug. In the crystal structure, the drug mol­ecule is linked into a one-dimensional structure along the c axis by weak N—H⋯O inter­actions between the amide groups. C—H⋯O and C—H⋯π inter­actions influence the packing.
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spelling pubmed-29620702010-12-30 2-Methoxy­phenyl 2-{2-[1-methyl-5-(4-methyl­benzo­yl)pyrrol-2-yl]acetamido}acetate Lou, Ben-Yong Guo, Xia Lin, Qi Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, amtolmetin guacil, C(24)H(24)N(2)O(5), is a new gastroprotective non-steroidal anti-inflammatory drug. In the crystal structure, the drug mol­ecule is linked into a one-dimensional structure along the c axis by weak N—H⋯O inter­actions between the amide groups. C—H⋯O and C—H⋯π inter­actions influence the packing. International Union of Crystallography 2008-07-09 /pmc/articles/PMC2962070/ /pubmed/21203154 http://dx.doi.org/10.1107/S1600536808020722 Text en © Lou et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Lou, Ben-Yong
Guo, Xia
Lin, Qi
2-Methoxy­phenyl 2-{2-[1-methyl-5-(4-methyl­benzo­yl)pyrrol-2-yl]acetamido}acetate
title 2-Methoxy­phenyl 2-{2-[1-methyl-5-(4-methyl­benzo­yl)pyrrol-2-yl]acetamido}acetate
title_full 2-Methoxy­phenyl 2-{2-[1-methyl-5-(4-methyl­benzo­yl)pyrrol-2-yl]acetamido}acetate
title_fullStr 2-Methoxy­phenyl 2-{2-[1-methyl-5-(4-methyl­benzo­yl)pyrrol-2-yl]acetamido}acetate
title_full_unstemmed 2-Methoxy­phenyl 2-{2-[1-methyl-5-(4-methyl­benzo­yl)pyrrol-2-yl]acetamido}acetate
title_short 2-Methoxy­phenyl 2-{2-[1-methyl-5-(4-methyl­benzo­yl)pyrrol-2-yl]acetamido}acetate
title_sort 2-methoxy­phenyl 2-{2-[1-methyl-5-(4-methyl­benzo­yl)pyrrol-2-yl]acetamido}acetate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962070/
https://www.ncbi.nlm.nih.gov/pubmed/21203154
http://dx.doi.org/10.1107/S1600536808020722
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AT guoxia 2methoxyphenyl221methyl54methylbenzoylpyrrol2ylacetamidoacetate
AT linqi 2methoxyphenyl221methyl54methylbenzoylpyrrol2ylacetamidoacetate

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